The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling.

The protein tyrosine phosphatase CD45 is a critical component of the T cell antigen receptor (TCR) signaling pathway, acting as a positive regulator of Src family protein tyrosine kinases (PTKs) such as Lck. Most CD45-deficient human and murine T cell lines are unable to signal through their TCRs. H...

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Bibliografske podrobnosti
Main Authors: Chu, D H, Spits, H, Peyron, J F, Rowley, R B, Bolen, J B, Weiss, A
Format: Artigo
Jezik:English
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC452448/
https://ncbi.nlm.nih.gov/pubmed/8947048
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC452448/
https://ncbi.nlm.nih.gov/pubmed/8947048

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