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CD40L expression permits CD8(+) T cells to execute immunologic helper functions

CD8(+) T cells play an essential role in immunity against intracellular pathogens, with cytotoxicity being considered their major effector mechanism. However, we here demonstrate that a major part of central and effector memory CD8(+) T cells expresses CD40L, one key molecule for CD4(+) T-cell–media...

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Natura: Articolo
Lingua:en
Pubblicazione: American Society of Hematology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548794/
https://ncbi.nlm.nih.gov/pubmed/23719298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-483586
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