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Increased ribosomal accuracy increases a programmed translational frameshift in Escherichia coli.

We have tested the effect of increased ribosomal fidelity on a modified version of the programmed release factor 2 (RF2) translational frameshift. In the constructs tested, the original UGA codon at the site of the shift was replaced by either of two sense codons, UGG (tryptophan), which allows a fr...

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Autori principali: Sipley, J, Goldman, E
Natura: Articolo
Lingua:en
Pubblicazione: 1993
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC46077/
https://ncbi.nlm.nih.gov/pubmed/8460140
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