Mitogenic activation of the Ras guanine nucleotide exchange factor in NIH 3T3 cells involves protein tyrosine phosphorylation.

We report biochemical evidence that epidermal growth factor and platelet-derived growth factor stimulate the Ras guanine nucleotide exchange factor activity in quiescent NIH 3T3 cells. Moreover, the exchange activity is constitutively enhanced in NIH 3T3 cells transformed by Src and ErbB2 oncogenic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Li, B Q, Subleski, M, Shalloway, D, Kung, H F, Kamata, T
Formatua: Artikulua
Hizkuntza:en
Argitaratua: 1993
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC47385/
https://ncbi.nlm.nih.gov/pubmed/8104337
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC47385/
https://ncbi.nlm.nih.gov/pubmed/8104337

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