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Microglia-Derived Cytokines/Chemokines Are Involved in the Enhancement of LPS-Induced Loss of Nigrostriatal Dopaminergic Neurons in DJ-1 Knockout Mice
Mutation of DJ-1 (PARK7) has been linked to the development of early-onset Parkinson’s disease (PD). However, the underlying molecular mechanism is still unclear. This study is aimed to compare the sensitivity of nigrostriatal dopaminergic neurons to lipopolysaccharide (LPS) challenge between DJ-1 k...
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| Format: | Article |
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| Language: | en |
| Published: |
Public Library of Science
2016
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4794203/ https://ncbi.nlm.nih.gov/pubmed/26982707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0151569 |
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