Structural alterations of the epidermal growth factor receptor gene in human gliomas.

The epidermal growth factor receptor (EGFR) gene is amplified in 40% of malignant gliomas, and the amplified genes are frequently rearranged. We have characterized the genetic alterations associated with these rearrangements in five malignant gliomas. In one tumor the rearrangement resulted in the d...

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Bibliografski detalji
Glavni autori: Wong, A J, Ruppert, J M, Bigner, S H, Grzeschik, C H, Humphrey, P A, Bigner, D S, Vogelstein, B
Format: Članak
Jezik:en
Izdano: 1992
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC48784/
https://ncbi.nlm.nih.gov/pubmed/1557402
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https://ncbi.nlm.nih.gov/pmc/articles/PMC48784/
https://ncbi.nlm.nih.gov/pubmed/1557402

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