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Vicinal cysteines in the prosequence play a role in von Willebrand factor multimer assembly.

von Willebrand factor (vWf) is synthesized as a large precursor that dimerizes in the endoplasmic reticulum and forms multimers in the trans- and post-Golgi compartments of megakaryocytes and endothelial cells. The disulfide-bonded multimers are stored in alpha granules of platelets and Weibel-Palad...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mayadas, T N, Wagner, D D
Formatua: Artikulua
Hizkuntza:en
Argitaratua: 1992
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC48902/
https://ncbi.nlm.nih.gov/pubmed/1565649
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