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Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes

Cancer is often driven by the accumulation of genetic alterations, including single nucleotide variants, small insertions or deletions, gene fusions, copy-number variations, and large chromosomal rearrangements. Recent advances in next-generation sequencing technologies have helped investigators gen...

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Detalles Bibliográficos
Formato: Artigo
Idioma:en
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945827/
https://ncbi.nlm.nih.gov/pubmed/26307061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv068
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