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Advances in computational approaches for prioritizing driver mutations and significantly mutated genes in cancer genomes

Cancer is often driven by the accumulation of genetic alterations, including single nucleotide variants, small insertions or deletions, gene fusions, copy-number variations, and large chromosomal rearrangements. Recent advances in next-generation sequencing technologies have helped investigators gen...

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Formaat: Artikel
Taal:en
Gepubliceerd in: Oxford University Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4945827/
https://ncbi.nlm.nih.gov/pubmed/26307061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbv068
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