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Atypical parkinsonism–associated retromer mutant alters endosomal sorting of specific cargo proteins

The retromer complex acts as a scaffold for endosomal protein complexes that sort integral membrane proteins to various cellular destinations. The retromer complex is a heterotrimer of VPS29, VPS35, and VPS26. Two of these paralogues, VPS26A and VPS26B, are expressed in humans. Retromer dysfunction...

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Format: Article
Idioma:en
Publicat: The Rockefeller University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987296/
https://ncbi.nlm.nih.gov/pubmed/27528657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604057
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