RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability.

Xeroderma pigmentosum (XP) patients are extremely sensitive to ultraviolet (UV) light and suffer from a high incidence of skin cancers, due to a defect in nucleotide excision repair. The disease is genetically heterogeneous, and seven complementation groups, A-G, have been identified. Homologs of hu...

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Bibliografiske detaljer
Main Authors: Park, E, Guzder, S N, Koken, M H, Jaspers-Dekker, I, Weeda, G, Hoeijmakers, J H, Prakash, S, Prakash, L
Format: Artigo
Sprog:en
Udgivet: 1992
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC50561/
https://ncbi.nlm.nih.gov/pubmed/1333609
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC50561/
https://ncbi.nlm.nih.gov/pubmed/1333609

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