A requirement for the rac1 GTPase in the signal transduction pathway leading to cardiac myocyte hypertrophy.

We have used adenoviral-mediated gene transfer of a constitutively active (V12rac1) and dominant negative (N17rac1) isoform of rac1 to assess the role of this small GTPase in cardiac myocyte hypertrophy. Expression of V12rac1 in neonatal cardiac myocytes results in sarcomeric reorganization and an i...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pracyk, J B, Tanaka, K, Hegland, D D, Kim, K S, Sethi, R, Rovira, I I, Blazina, D R, Lee, L, Bruder, J T, Kovesdi, I, Goldshmidt-Clermont, P J, Irani, K, Finkel, T
Formatua: Artikulua
Hizkuntza:English
Argitaratua: 1998
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC508958/
https://ncbi.nlm.nih.gov/pubmed/9727061
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC508958/
https://ncbi.nlm.nih.gov/pubmed/9727061

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