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Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch

Lysine demethylation of proteins such as histones is catalyzed by several classes of enzymes, including the FAD-dependent amine oxidases KDM1A/B. The KDM1 family is homologous to the mitochondrial monoamine oxidases MAO-A/B and produces hydrogen peroxide in the nucleus as a byproduct of demethylatio...

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Bibliografiset tiedot
Aineistotyyppi: Artikkeli
Kieli:en
Julkaistu: American Society for Biochemistry and Molecular Biology 2016
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114423/
https://ncbi.nlm.nih.gov/pubmed/27634040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734426
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