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β-Arrestin-1 Competitively Inhibits Insulin-Induced Ubiquitination and Degradation of Insulin Receptor Substrate 1
β-Arrestin-1 is an adaptor protein that mediates agonist-dependent internalization and desensitization of G-protein-coupled receptors (GPCRs) and also participates in the process of heterologous desensitization between receptor tyrosine kinases and GPCR signaling. In the present study, we determined...
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| Autori principali: | , , , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
American Society for Microbiology
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC517874/ https://ncbi.nlm.nih.gov/pubmed/15456867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.20.8929-8937.2004 |
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