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Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription.
Investigations of the actions and interactions of the immunophilin ligands FK506, cyclosporin A (CsA), rapamycin, and 506BD suggest that complexes of FK506 with an FK506-binding protein or of CsA with a cyclophilin (CsA-binding protein) inhibit the T-cell receptor-mediated signal transduction that r...
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| Hlavní autoři: | , , , |
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| Médium: | Článek |
| Jazyk: | en |
| Vydáno: |
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC52056/ https://ncbi.nlm.nih.gov/pubmed/1712484 |
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