Decreased Bioavailability of Rifampin and Other Antituberculosis Drugs in Patients with Advanced Human Immunodeficiency Virus Disease

We evaluated the effects of human immunodeficiency virus (HIV) disease on pharmacokinetics of antituberculosis medications by measuring concentrations of isoniazid and rifampin in blood and of pyrazinamide and ethambutol in urine. Peak concentration and exposure were reduced for rifampin, and rapid...

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Bibliografiske detaljer
Main Authors: Gurumurthy, Prema, Ramachandran, Geetha, Hemanth Kumar, A. K., Rajasekaran, S., Padmapriyadarsini, C., Swaminathan, Soumya, Bhagavathy, S., Venkatesan, P., Sekar, L., Mahilmaran, A., Ravichandran, N., Paramesh, P.
Format: Artigo
Sprog:English
Udgivet: American Society for Microbiology 2004
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC525439/
https://ncbi.nlm.nih.gov/pubmed/15504887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4473-4475.2004
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC525439/
https://ncbi.nlm.nih.gov/pubmed/15504887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4473-4475.2004

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