Effect of Antacids and Ranitidine on the Single-Dose Pharmacokinetics of Fosamprenavir

Single doses of MAALOX TC and ranitidine were administered separately with 1,400 mg of fosamprenavir (FPV). MAALOX TC decreased the area under the concentration-time curve from 0 to 24 h (AUC(0-24)) for plasma amprenavir (APV) by 18% and the maximum concentration of drug in serum (C(max)) by 35%; th...

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Bibliografiske detaljer
Main Authors: Ford, Susan L., Wire, Mary B., Lou, Yu, Baker, Katherine L., Stein, Daniel S.
Format: Artigo
Sprog:English
Udgivet: American Society for Microbiology 2005
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538899/
https://ncbi.nlm.nih.gov/pubmed/15616339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.467-469.2005
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC538899/
https://ncbi.nlm.nih.gov/pubmed/15616339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.1.467-469.2005

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