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ROG Negatively Regulates T-Cell Activation but Is Dispensable for Th-Cell Differentiation
ROG, a transcriptional repressor, is a direct target gene of NF-AT and a putative negative regulator of T-cell activation. In addition, overexpression of ROG suppresses the activity of GATA-3, implying a role of ROG in the differentiation and function of Th cells. Despite these observations, the fun...
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| Autors principals: | , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
American Society for Microbiology
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC543427/ https://ncbi.nlm.nih.gov/pubmed/15632058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.554-562.2005 |
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