A Type IV Pilin, PilA, Contributes to Adherence of Burkholderia pseudomallei and Virulence In Vivo

The Burkholderia pseudomallei K96243 genome contains multiple type IV pilin-associated loci, including one encoding a putative pilus structural protein (pilA). A pilA deletion mutant has reduced adherence to human epithelial cells and is less virulent in the nematode model of virulence and the murin...

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Hlavní autoři: Essex-Lopresti, Angela E., Boddey, Justin A., Thomas, Richard, Smith, Martin P., Hartley, M. Gill, Atkins, Timothy, Brown, Nat F., Tsang, Chuk Hai, Peak, Ian R. A., Hill, Jim, Beacham, Ifor R., Titball, Richard W.
Médium: Článek
Jazyk:English
Vydáno: American Society for Microbiology 2005
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC547011/
https://ncbi.nlm.nih.gov/pubmed/15664977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.1260-1264.2005
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https://ncbi.nlm.nih.gov/pmc/articles/PMC547011/
https://ncbi.nlm.nih.gov/pubmed/15664977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.2.1260-1264.2005

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