Sugar additives for MALDI matrices improve signal allowing the smallest nucleotide change (A:T) in a DNA sequence to be resolved

Sample preparation for matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) of DNA is critical for obtaining high quality mass spectra. Sample impurity, solvent content, substrate surface and environmental conditions (temperature and humidity) all affect the rate of matrix–anal...

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Bibliografische gegevens
Hoofdauteurs: Shahgholi, Mona, Garcia, Benjamin A., Chiu, Norman H. L., Heaney, Paul J., Tang, Kai
Formaat: Artikel
Taal:en
Gepubliceerd in: Oxford University Press 2001
Onderwerpen:
NAR Methods Online
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC60251/
https://ncbi.nlm.nih.gov/pubmed/11574693
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC60251/
https://ncbi.nlm.nih.gov/pubmed/11574693

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