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LAT Is Required for Tyrosine Phosphorylation of Phospholipase Cγ2 and Platelet Activation by the Collagen Receptor GPVI

In the present study, we have addressed the role of the linker for activation of T cells (LAT) in the regulation of phospholipase Cγ2 (PLCγ2) by the platelet collagen receptor glycoprotein VI (GPVI). LAT is tyrosine phosphorylated in human platelets heavily in response to collagen, collagen-related...

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Autors principals: Pasquet, Jean-Max, Gross, Barbara, Quek, Lynn, Asazuma, Naoki, Zhang, Weiguo, Sommers, Connie L., Schweighoffer, Edina, Tybulewicz, Victor, Judd, Barbara, Lee, Jong Ran, Koretzky, Gary, Love, Paul E., Samelson, Lawrence E., Watson, Steve P.
Format: Article
Idioma:en
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84916/
https://ncbi.nlm.nih.gov/pubmed/10567557
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