Dynamic Analysis of Proviral Induction and De Novo Methylation: Implications for a Histone Deacetylase-Independent, Methylation Density-Dependent Mechanism of Transcriptional Repression

Methylation of cytosines in the CpG dinucleotide is generally associated with transcriptional repression in mammalian cells, and recent findings implicate histone deacetylation in methylation-mediated repression. Analyses of histone acetylation in in vitro-methylated transfected plasmids support thi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lorincz, Matthew C., Schübeler, Dirk, Goeke, Scott C., Walters, Mark, Groudine, Mark, Martin, David I. K.
Natura: Articolo
Lingua:en
Pubblicazione: American Society for Microbiology 2000
Soggetti:
Transcriptional Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC85201/
https://ncbi.nlm.nih.gov/pubmed/10629041
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Accesso online

https://ncbi.nlm.nih.gov/pmc/articles/PMC85201/
https://ncbi.nlm.nih.gov/pubmed/10629041

Documenti analoghi