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Position Effects Are Influenced by the Orientation of a Transgene with Respect to Flanking Chromatin
We have inserted two expression cassettes at tagged reference chromosomal sites by using recombinase-mediated cassette exchange in mammalian cells. The three sites of integration displayed either stable or silencing position effects that were dominant over the different enhancers present in the cass...
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| Auteurs principaux: | , , , , |
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| Format: | Article |
| Langue: | en |
| Publié: |
American Society for Microbiology
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC88803/ https://ncbi.nlm.nih.gov/pubmed/11113204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.298-309.2001 |
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