Treatment of Tuberculosis Using a Combination of Sustained-Release Rifampin-Loaded Microspheres and Oral Dosing with Isoniazid

Previously, we reported on the use of rifampin-loaded microspheres to effectively treat Mycobacterium tuberculosis-infected macrophages and mice. Using similar biocompatible polymeric excipients of lactide and glycolide copolymers, we have increased the rifampin loading of small microsphere formulat...

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Hlavní autoři: Quenelle, Debra C., Winchester, Gary A., Staas, Jay K., Barrow, Esther L. W., Barrow, William W.
Médium: Článek
Jazyk:en
Vydáno: American Society for Microbiology 2001
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90525/
https://ncbi.nlm.nih.gov/pubmed/11353605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1637-1644.2001
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https://ncbi.nlm.nih.gov/pmc/articles/PMC90525/
https://ncbi.nlm.nih.gov/pubmed/11353605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1637-1644.2001

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