Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis

The complete Bacillus subtilis genome contains four genes (proG, proH, proI, and comER) with the potential to encode Δ(1)-pyrroline-5-carboxylate reductase, a proline biosynthetic enzyme. Simultaneous defects in three of these genes (proG, proH, and proI) were required to confer proline auxotrophy,...

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Main Authors: Belitsky, Boris R., Brill, Jeanette, Bremer, Erhard, Sonenshein, Abraham L.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology 2001
Assuntos:
Physiology and Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC95331/
https://ncbi.nlm.nih.gov/pubmed/11418582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.14.4389-4392.2001
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spelling pubmed-953312002-09-13 Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis Belitsky, Boris R. Brill, Jeanette Bremer, Erhard Sonenshein, Abraham L. J Bacteriol Physiology and Metabolism The complete Bacillus subtilis genome contains four genes (proG, proH, proI, and comER) with the potential to encode Δ(1)-pyrroline-5-carboxylate reductase, a proline biosynthetic enzyme. Simultaneous defects in three of these genes (proG, proH, and proI) were required to confer proline auxotrophy, indicating that the products of these genes are mostly interchangeable with respect to the last step in proline biosynthesis. American Society for Microbiology 2001-07 /pmc/articles/PMC95331/ /pubmed/11418582 http://dx.doi.org/10.1128/JB.183.14.4389-4392.2001 Text en Copyright © 2001, American Society for Microbiology
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Physiology and Metabolism
spellingShingle Physiology and Metabolism
Belitsky, Boris R.
Brill, Jeanette
Bremer, Erhard
Sonenshein, Abraham L.
Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis
description The complete Bacillus subtilis genome contains four genes (proG, proH, proI, and comER) with the potential to encode Δ(1)-pyrroline-5-carboxylate reductase, a proline biosynthetic enzyme. Simultaneous defects in three of these genes (proG, proH, and proI) were required to confer proline auxotrophy, indicating that the products of these genes are mostly interchangeable with respect to the last step in proline biosynthesis.
author Belitsky, Boris R.
Brill, Jeanette
Bremer, Erhard
Sonenshein, Abraham L.
author_facet Belitsky, Boris R.
Brill, Jeanette
Bremer, Erhard
Sonenshein, Abraham L.
author_sort Belitsky, Boris R.
title Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis
title_short Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis
title_full Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis
title_fullStr Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis
title_full_unstemmed Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis
title_sort multiple genes for the last step of proline biosynthesis in bacillus subtilis
publisher American Society for Microbiology
publisher_facet American Society for Microbiology
publishDate 2001
url https://ncbi.nlm.nih.gov/pmc/articles/PMC95331/
https://ncbi.nlm.nih.gov/pubmed/11418582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.14.4389-4392.2001
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