TY - JOUR T1 - Multiple Genes for the Last Step of Proline Biosynthesis in Bacillus subtilis A1 - Belitsky, Boris R. LA - en PB - American Society for Microbiology YR - 2001 UL - http://buscaintegrada.pucsp.br/vufind/Record/pubmed-95331 AB - The complete Bacillus subtilis genome contains four genes (proG, proH, proI, and comER) with the potential to encode Δ(1)-pyrroline-5-carboxylate reductase, a proline biosynthetic enzyme. Simultaneous defects in three of these genes (proG, proH, and proI) were required to confer proline auxotrophy, indicating that the products of these genes are mostly interchangeable with respect to the last step in proline biosynthesis. KW - Physiology and Metabolism ER -