Shigella flexneri IpaH(7.8) Facilitates Escape of Virulent Bacteria from the Endocytic Vacuoles of Mouse and Human Macrophages

The behavior of Shigella flexneri ipaH mutants was studied in human monocyte-derived macrophages (HMDM), in 1-day-old human monocytes, and in J774 mouse macrophage cell line. In HMDM, strain pWR700, an ipaH(7.8) deletion mutant of S. flexneri 2a strain 2457T, behaved like the wild-type strain 2457T....

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Hauptverfasser: Fernandez-Prada, Carmen M., Hoover, David L., Tall, Ben D., Hartman, Antoinette B., Kopelowitz, June, Venkatesan, Malabi M.
Format: Artikel
Sprache:en
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Molecular and Cellular Pathogenesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC97650/
https://ncbi.nlm.nih.gov/pubmed/10816519
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https://ncbi.nlm.nih.gov/pmc/articles/PMC97650/
https://ncbi.nlm.nih.gov/pubmed/10816519

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