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Vibrio cholerae tolC Is Required for Bile Resistance and Colonization

TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobi...

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Main Authors: Bina, James E., Mekalanos, John J.
Formato: Artigo
Idioma:en
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98549/
https://ncbi.nlm.nih.gov/pubmed/11402016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001
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spelling pubmed-985492002-09-12 Vibrio cholerae tolC Is Required for Bile Resistance and Colonization Bina, James E. Mekalanos, John J. Infect Immun Molecular Pathogenesis TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobial agents, and were deficient in intestinal colonization. American Society for Microbiology (ASM) 2001-07 /pmc/articles/PMC98549/ /pubmed/11402016 http://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001 Text en Copyright © 2001, American Society for Microbiology
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Molecular Pathogenesis
spellingShingle Molecular Pathogenesis
Bina, James E.
Mekalanos, John J.
Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
description TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobial agents, and were deficient in intestinal colonization.
author Bina, James E.
Mekalanos, John J.
author_facet Bina, James E.
Mekalanos, John J.
author_sort Bina, James E.
title Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
title_short Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
title_full Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
title_fullStr Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
title_full_unstemmed Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
title_sort vibrio cholerae tolc is required for bile resistance and colonization
publisher American Society for Microbiology (ASM)
publisher_facet American Society for Microbiology (ASM)
publishDate 2001
url https://ncbi.nlm.nih.gov/pmc/articles/PMC98549/
https://ncbi.nlm.nih.gov/pubmed/11402016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001
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