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Vibrio cholerae tolC Is Required for Bile Resistance and Colonization
TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobi...
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| Формат: | Стаття |
| Мова: | en |
| Опубліковано: |
American Society for Microbiology (ASM)
2001
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| Онлайн доступ: | https://ncbi.nlm.nih.gov/pmc/articles/PMC98549/ https://ncbi.nlm.nih.gov/pubmed/11402016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001 |
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pubmed-985492002-09-12 Vibrio cholerae tolC Is Required for Bile Resistance and Colonization Bina, James E. Mekalanos, John J. Infect Immun Molecular Pathogenesis TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobial agents, and were deficient in intestinal colonization. American Society for Microbiology (ASM) 2001-07 /pmc/articles/PMC98549/ /pubmed/11402016 http://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001 Text en Copyright © 2001, American Society for Microbiology |
| institution |
US National Library of Medicine |
| collection |
PubMed Central |
| language |
en |
| format |
Article |
| topic |
Molecular Pathogenesis |
| spellingShingle |
Molecular Pathogenesis Bina, James E. Mekalanos, John J. Vibrio cholerae tolC Is Required for Bile Resistance and Colonization |
| description |
TolC and its homologues are outer membrane proteins that are essential for the transport of many molecules across the cell envelope. In this study we characterized the gene encoding Vibrio cholerae TolC. V. cholerae tolC mutants failed to secrete the RTX cytotoxin, were hypersensitive to antimicrobial agents, and were deficient in intestinal colonization. |
| author |
Bina, James E. Mekalanos, John J. |
| author_facet |
Bina, James E. Mekalanos, John J. |
| author_sort |
Bina, James E. |
| title |
Vibrio cholerae tolC Is Required for Bile
Resistance and Colonization |
| title_short |
Vibrio cholerae tolC Is Required for Bile
Resistance and Colonization |
| title_full |
Vibrio cholerae tolC Is Required for Bile
Resistance and Colonization |
| title_fullStr |
Vibrio cholerae tolC Is Required for Bile
Resistance and Colonization |
| title_full_unstemmed |
Vibrio cholerae tolC Is Required for Bile
Resistance and Colonization |
| title_sort |
vibrio cholerae tolc is required for bile
resistance and colonization |
| publisher |
American Society for Microbiology (ASM) |
| publisher_facet |
American Society for Microbiology (ASM) |
| publishDate |
2001 |
| url |
https://ncbi.nlm.nih.gov/pmc/articles/PMC98549/ https://ncbi.nlm.nih.gov/pubmed/11402016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001 |
| _version_ |
1759030606160723968 |