Bibliotecas PUC-SP - Busca Integrada

Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes

door Maikel L. Colli, Florian Szymczak, Decio L. Eizirik, Decio L. Eizirik, Decio L. Eizirik
Gepubliceerd in Frontiers in Endocrinology (2020-09-01)

β‐Cell gene expression stress signatures in types 1 and 2 diabetes

door Xiaoyan Yi, Decio L. Eizirik
Gepubliceerd in Journal of Diabetes (2024-11-01)

Clic4, a novel protein that sensitizes β-cells to apoptosis

door Dhaval Patel, Damien Ythier, Flora Brozzi, Decio L. Eizirik, Bernard Thorens
Gepubliceerd in Molecular Metabolism (2015-04-01)

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells.

door Esteban N Gurzov, Fernanda Ortis, Latifa Bakiri, Erwin F Wagner, Decio L Eizirik
Gepubliceerd in PLoS ONE (2008-01-01)

Pro-inflammatory cytokines induce cell death, inflammatory responses, and endoplasmic reticulum stress in human iPSC-derived beta cells

door Stéphane Demine, Andrea Alex Schiavo, Sandra Marín-Cañas, Piero Marchetti, Miriam Cnop, Decio L. Eizirik
Gepubliceerd in Stem Cell Research & Therapy (2020-01-01)

BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis

door Atenea A. Perez-Serna, Reinaldo S. Dos Santos, Cristina Ripoll, Angel Nadal, Decio L. Eizirik, Laura Marroqui
Gepubliceerd in International Journal of Molecular Sciences (2023-03-01)

The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells.

door Fabrice Moore, Izortze Santin, Tatiane C Nogueira, Esteban N Gurzov, Lorella Marselli, Piero Marchetti, Decio L Eizirik
Gepubliceerd in PLoS ONE (2012-01-01)

Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies

door Xiaoyan Yi, Bianca Marmontel de Souza, Toshiaki Sawatani, Florian Szymczak, Lorella Marselli, Piero Marchetti, Miriam Cnop, Decio L. Eizirik
Gepubliceerd in iScience (2022-11-01)

A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes

door Sandrine Luce, Sandrine Luce, Sophie Guinoiseau, Sophie Guinoiseau, Alexis Gadault, Alexis Gadault, Franck Letourneur, Patrick Nitschke, Marc Bras, Michel Vidaud, Pierre Charneau, Etienne Larger, Etienne Larger, Maikel L. Colli, Decio L. Eizirik, Decio L. Eizirik, François Lemonnier, François Lemonnier, Christian Boitard, Christian Boitard, Christian Boitard
Gepubliceerd in Frontiers in Immunology (2021-10-01)

Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes

door Laura Marroqui, Matilde Masini, Beatriz Merino, Fabio A. Grieco, Isabelle Millard, Christine Dubois, Ivan Quesada, Piero Marchetti, Miriam Cnop, Decio L. Eizirik
Gepubliceerd in EBioMedicine (2015-05-01)

Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells

door Simranjeet Kaur, Caroline Frørup, Aashiq H. Mirza, Tina Fløyel, Reza Yarani, Maikel L. Colli, Jesper Johannesen, Joachim Størling, Decio L. Eizirik, Flemming Pociot
Gepubliceerd in Non-Coding RNA (2022-10-01)

SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature

door Daniela Fignani, Daniela Fignani, Giada Licata, Giada Licata, Noemi Brusco, Noemi Brusco, Laura Nigi, Laura Nigi, Giuseppina E. Grieco, Giuseppina E. Grieco, Lorella Marselli, Lut Overbergh, Conny Gysemans, Maikel L. Colli, Piero Marchetti, Chantal Mathieu, Decio L. Eizirik, Decio L. Eizirik, Guido Sebastiani, Guido Sebastiani, Francesco Dotta, Francesco Dotta, Francesco Dotta
Gepubliceerd in Frontiers in Endocrinology (2020-11-01)

Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.

door Maikel L Colli, Tatiane C Nogueira, Florent Allagnat, Daniel A Cunha, Esteban N Gurzov, Alessandra K Cardozo, Merja Roivainen, Anne Op de Beeck, Decio L Eizirik
Gepubliceerd in PLoS Pathogens (2011-09-01)

Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells

door Laura Marroqui, Miguel Lopes, Reinaldo S dos Santos, Fabio A Grieco, Merja Roivainen, Sarah J Richardson, Noel G Morgan, Anne Op de beeck, Decio L Eizirik
Gepubliceerd in eLife (2015-06-01)

The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes

door Tania Quesada-López, Rubén Cereijo, Jean-Valery Turatsinze, Anna Planavila, Montserrat Cairó, Aleix Gavaldà-Navarro, Marion Peyrou, Ricardo Moure, Roser Iglesias, Marta Giralt, Decio L. Eizirik, Francesc Villarroya
Gepubliceerd in Nature Communications (2016-11-01)

GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim.

door Tatiane C Nogueira, Flavia M Paula, Olatz Villate, Maikel L Colli, Rodrigo F Moura, Daniel A Cunha, Lorella Marselli, Piero Marchetti, Miriam Cnop, Cécile Julier, Decio L Eizirik
Gepubliceerd in PLoS Genetics (2013-05-01)

The N6-methyladenosine RNA epigenetic modification modulates the amplification of coxsackievirus B1 in human pancreatic beta cells

door Maressa Fernandes Bonfim, Camille Aitchedji, Flore Van Goethem, Lionel Sauvage, Thibault Poinsot, Emilie Calonne, Rachel Deplus, François Fuks, Decio L. Eizirik, Anne Op de Beeck, Anne Op de Beeck
Gepubliceerd in Frontiers in Microbiology (2024-12-01)

Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis

door Marta Tesi, Marco Bugliani, Gianmarco Ferri, Mara Suleiman, Carmela De Luca, Emanuele Bosi, Matilde Masini, Vincenzo De Tata, Conny Gysemans, Francesco Cardarelli, Miriam Cnop, Decio L. Eizirik, Piero Marchetti, Lorella Marselli
Gepubliceerd in Biomolecules (2021-02-01)

Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa

door Stéphane Demine, Alexander Balhuizen, Vinciane Debaille, Lieke Joosten, Maïté Fereau, Satya Narayana Murthy Chilla, Isabelle Millard, Raphaël Scharfmann, Dominique Egrise, Serge Goldman, Piero Marchetti, Martin Gotthardt, Sophie Laurent, Carmen Burtea, Decio L. Eizirik
Gepubliceerd in Molecules (2018-08-01)

Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity

door Maria Lytrivi, Kassem Ghaddar, Miguel Lopes, Victoria Rosengren, Anthony Piron, Xiaoyan Yi, Henrik Johansson, Janne Lehtiö, Mariana Igoillo-Esteve, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Henrik Ortsäter, Decio L. Eizirik, Miriam Cnop
Gepubliceerd in BMC Genomics (2020-08-01)