Bibliotecas PUC-SP - Busca Integrada

Modeling is Believing? How AlphaFold2 Can Mislead Molecular Interpretation

מאת Karly Forker, Matthew C Fleming, Kenneth H Pearce, Cyrus Vaziri, Albert Bowers, Pei Zhou
הוצא לאור ב Structural Dynamics (2025-10-01)

A novel small molecule screening assay using normal human chondrocytes toward osteoarthritis drug discovery.

מאת Philip R Coryell, Paul B Hardy, Susan Chubinskaya, Kenneth H Pearce, Richard F Loeser
הוצא לאור ב PLoS ONE (2024-01-01)

Development of a high-throughput TR-FRET screening assay for a fast-cycling KRAS mutant

מאת Jacob E. Larson, P. Brian Hardy, Noah K. Schomburg, Xiaodong Wang, Dmitri Kireev, Kent L. Rossman, Kenneth H. Pearce
הוצא לאור ב SLAS Discovery (2023-01-01)

In silico fragment-based discovery of CIB1-directed anti-tumor agents by FRASE-bot

מאת Yi An, Jiwoong Lim, Marta Glavatskikh, Xiaowen Wang, Jacqueline Norris-Drouin, P. Brian Hardy, Tina M. Leisner, Kenneth H. Pearce, Dmitri Kireev
הוצא לאור ב Nature Communications (2024-07-01)

A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors.

מאת Brandi M Baughman, Huanchen Wang, Yi An, Dmitri Kireev, Michael A Stashko, Henning J Jessen, Kenneth H Pearce, Stephen V Frye, Stephen B Shears
הוצא לאור ב PLoS ONE (2016-01-01)

Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors.

מאת Brandi M Baughman, Huanchen Wang, Yi An, Dmitri Kireev, Michael A Stashko, Henning J Jessen, Kenneth H Pearce, Stephen V Frye, Stephen B Shears
הוצא לאור ב PLoS ONE (2017-01-01)

Author Correction: A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

מאת Yanzhe Gao, Elizabeth Mutter-Rottmayer, Alicia M. Greenwalt, Dennis Goldfarb, Feng Yan, Yang Yang, Raquel C. Martinez-Chacin, Kenneth H. Pearce, Satoshi Tateishi, Michael B. Major, Cyrus Vaziri
הוצא לאור ב Nature Communications (2024-11-01)

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis

מאת Yanzhe Gao, Elizabeth Mutter-Rottmayer, Alicia M. Greenwalt, Dennis Goldfarb, Feng Yan, Yang Yang, Raquel C. Martinez-Chacin, Kenneth H. Pearce, Satoshi Tateishi, Michael B. Major, Cyrus Vaziri
הוצא לאור ב Nature Communications (2016-07-01)

Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins

מאת Kelsey N. Lamb, Sarah N. Dishman, Jarod M. Waybright, Isabelle A. Engelberg, Justin M. Rectenwald, Jacqueline L. Norris-Drouin, Stephanie H. Cholensky, Kenneth H. Pearce, Lindsey I. James, Stephen V. Frye
הוצא לאור ב ACS Omega (2021-12-01)

Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins

מאת Justin M. Rectenwald, Shiva Krishna Reddy Guduru, Zhao Dang, Leonard B. Collins, Yi-En Liao, Jacqueline L. Norris-Drouin, Stephanie H. Cholensky, Kyle W. Kaufmann, Scott M. Hammond, Dmitri B. Kireev, Stephen V. Frye, Kenneth H. Pearce
הוצא לאור ב Molecules (2020-02-01)

Discovery of hit compounds for methyl-lysine reader proteins from a target class DNA-encoded library

מאת Devan J. Shell, Justin M. Rectenwald, Peter H. Buttery, Rebecca L. Johnson, Caroline A. Foley, Shiva K.R. Guduru, Mélanie Uguen, Juanita Sanchez Rubiano, Xindi Zhang, Fengling Li, Jacqueline L. Norris-Drouin, Matthew Axtman, P. Brian Hardy, Masoud Vedadi, Stephen V. Frye, Lindsey I. James, Kenneth H. Pearce
הוצא לאור ב SLAS Discovery (2022-12-01)

Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

מאת Frances M. Bashore, Vittorio L. Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J. Bradshaw, Karolina A. Rygiel, Tina M. Leisner, Rod Chalk, Swati Mishra, C. Andrew Williams, Opher Gileadi, Paul E. Brennan, Jesse C. Wiley, Jake Gockley, Gregory A. Cary, Gregory W. Carter, Jessica E. Young, Kenneth H. Pearce, Haian Fu, Alison D. Axtman
הוצא לאור ב PLoS ONE (2024-01-01)

Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.

מאת Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman
הוצא לאור ב PLoS ONE (2024-01-01)

AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery

מאת Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce, Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman
הוצא לאור ב Alzheimer’s & Dementia: Translational Research & Clinical Interventions (2022-01-01)

Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology

מאת Frances M. Potjewyd, Joel K. Annor‐Gyamfi, Jeffrey Aubé, Shaoyou Chu, Ivie L. Conlon, Kevin J. Frankowski, Shiva K. R. Guduru, Brian P. Hardy, Megan D. Hopkins, Chizuru Kinoshita, Dmitri B. Kireev, Emily R. Mason, Charles T. Moerk, Felix Nwogbo, Kenneth H. Pearce Jr., Timothy I. Richardson, David A. Rogers, Disha M. Soni, Michael Stashko, Xiaodong Wang, Carrow Wells, Timothy M. Willson, Stephen V. Frye, Jessica E. Young, Alison D. Axtman
הוצא לאור ב Alzheimer’s & Dementia: Translational Research & Clinical Interventions (2022-01-01)

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine, and Pyronaridine: In Vitro Activity against SARS-CoV‑2 and Potential Mechanisms

מאת Ana C. Puhl, Ethan J. Fritch, Thomas R. Lane, Longping V. Tse, Boyd L. Yount, Carolina Q. Sacramento, Natalia Fintelman-Rodrigues, Tatyana Almeida Tavella, Fabio Trindade Maranhão Costa, Stuart Weston, James Logue, Matthew Frieman, Lakshmanane Premkumar, Kenneth H. Pearce, Brett L. Hurst, Carolina Horta Andrade, James A. Levi, Nicole J. Johnson, Samantha C. Kisthardt, Frank Scholle, Thiago Moreno L. Souza, Nathaniel John Moorman, Ralph S. Baric, Peter B. Madrid, Sean Ekins
הוצא לאור ב ACS Omega (2021-03-01)

Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells

מאת Mélanie Uguen, Devan J. Shell, Madhushika Silva, Yu Deng, Fengling Li, Magdalena M. Szewczyk, Ka Yang, Yani Zhao, Michael A. Stashko, Jacqueline L. Norris-Drouin, Jarod M. Waybright, Serap Beldar, Justin M. Rectenwald, Angie L. Mordant, Thomas S. Webb, Laura E. Herring, Cheryl H. Arrowsmith, Suzanne Ackloo, Steven P. Gygi, Robert K. McGinty, Dalia Barsyte-Lovejoy, Pengda Liu, Levon Halabelian, Lindsey I. James, Kenneth H. Pearce, Stephen V. Frye
הוצא לאור ב Nature Communications (2025-02-01)

A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity

מאת Anirban Ghoshal, Edwin G. Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M. Merten, John D. Sears, Stefanie Howell, Sumera Perveen, Jane Burdick, Noah L. Morales, Sabian A. Martinez, Isabella Law, Bennett J. Davenport, Thomas E. Morrison, Zachary J. Streblow, Daniel N. Streblow, Angie L. Mordant, Thomas S. Webb, Aurora Cabrera, Laura E. Herring, Cheryl H. Arrowsmith, Kenneth H. Pearce, Nathaniel J. Moorman, Mark T. Heise, Rafael M. Couñago, Peter J. Brown, Timothy M. Willson
הוצא לאור ב Scientific Reports (2025-03-01)