Bibliotecas PUC-SP - Busca Integrada

The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research.

par Jack Bowden, Luke C Pilling, Deniz Türkmen, Chia-Ling Kuo, David Melzer
Publié dans PLoS Genetics (2021-09-01)

Red cell distribution width and common disease onsets in 240,477 healthy volunteers followed for up to 9 years.

par Luke C Pilling, Janice L Atkins, George A Kuchel, Luigi Ferrucci, David Melzer
Publié dans PLoS ONE (2018-01-01)

Hemochromatosis Genetic Variants and Musculoskeletal Outcomes: 11.5‐Year Follow‐Up in the UK Biobank Cohort Study

par Lucy R. Banfield, Karen M. Knapp, Luke C. Pilling, David Melzer, Janice L. Atkins
Publié dans JBMR Plus (2023-10-01)

HFE genotypes, haemochromatosis diagnosis and clinical outcomes at age 80 years: a prospective cohort study in the UK Biobank

par Luke C Pilling, David Melzer, Janice L Atkins, Mitchell R Lucas, Jeremy D Shearman
Publié dans BMJ Open (2024-03-01)

Understanding the causes and consequences of low statin adherence: evidence from UK Biobank primary care data

par Deniz Türkmen, Xiaoran Liang, Jane A. H. Masoli, Dipender Gill, Luke C. Pilling, Jack Bowden
Publié dans BMC Medicine (2025-07-01)

Association between Residential Exposure to Air Pollution and Incident Coronary Heart Disease Is Not Mediated by Leukocyte Telomere Length: A UK Biobank Study

par Chia-Ling Kuo, Rui Liu, Lucas da Cunha Godoy, Luke C. Pilling, Richard H. Fortinsky, Doug Brugge
Publié dans Toxics (2023-05-01)

Very Low and High Levels of Vitamin D Are Associated with Shorter Leukocyte Telomere Length in 148,321 UK Biobank Participants

par Chia-Ling Kuo, Ben Kirk, Meiruo Xiang, Luke C. Pilling, George A. Kuchel, Richard Kremer, Gustavo Duque
Publié dans Nutrients (2023-03-01)

MRI-derived brain iron, grey matter volume, and risk of dementia and Parkinson's disease: Observational and genetic analysis in the UK Biobank cohort

par Francesco Casanova, Qu Tian, Daniel S. Williamson, Yong Qian, David Zweibaum, Jun Ding, Janice L. Atkins, David Melzer, Luigi Ferrucci, Luke C. Pilling
Publié dans Neurobiology of Disease (2024-07-01)

Analysis of CYP2C19 genetic variants with ischaemic events in UK patients prescribed clopidogrel in primary care: a retrospective cohort study

par Luke C Pilling, George A Kuchel, Luigi Ferrucci, David Melzer, Janice L Atkins, João Delgado, Jack Bowden, Deniz Türkmen, Hannah Fullalove, Chia-Ling Kuo, Jane A H Masoli
Publié dans BMJ Open (2021-12-01)

Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

par Luke C Pilling, Janice L Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer
Publié dans PLoS ONE (2017-01-01)

Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience

par Keenan A. Walker, Yang An, Abhay Moghekar, Ruin Moaddel, Michael R. Duggan, Zhongsheng Peng, Qu Tian, Luke C. Pilling, Shannon M. Drouin, Mark A. Espeland, Stephen R Rapp, Kathleen M Hayden, Aladdin H. Shadyab, Ramon Casanova, Madhav Thambisetty, Peter R. Rapp, Dimitrios Kapogiannis, Luigi Ferrucci, Susan M. Resnick
Publié dans Molecular Neurodegeneration (2024-10-01)

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context

par Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado
Publié dans EBioMedicine (2025-03-01)

A meta-analysis of gene expression signatures of blood pressure and hypertension.

par Tianxiao Huan, Tõnu Esko, Marjolein J Peters, Luke C Pilling, Katharina Schramm, Claudia Schurmann, Brian H Chen, Chunyu Liu, Roby Joehanes, Andrew D Johnson, Chen Yao, Sai-Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G Uitterlinden, Dena G Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger, Marcus Dörr, Stephan B Felix, Tanja Zeller, International Consortium for Blood Pressure GWAS (ICBP), Ramachandran Vasan, Christopher J O'Donnell, Peter J Munson, Xia Yang, Holger Prokisch, Uwe Völker, Joyce B J van Meurs, Luigi Ferrucci, Daniel Levy
Publié dans PLoS Genetics (2015-03-01)

Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women

par Garan Jones, Katerina Trajanoska, Adam J. Santanasto, Najada Stringa, Chia-Ling Kuo, Janice L. Atkins, Joshua R. Lewis, ThuyVy Duong, Shengjun Hong, Mary L. Biggs, Jian’an Luan, Chloe Sarnowski, Kathryn L. Lunetta, Toshiko Tanaka, Mary K. Wojczynski, Ryan Cvejkus, Maria Nethander, Sahar Ghasemi, Jingyun Yang, M. Carola Zillikens, Stefan Walter, Kamil Sicinski, Erika Kague, Cheryl L. Ackert-Bicknell, Dan E. Arking, B. Gwen Windham, Eric Boerwinkle, Megan L. Grove, Misa Graff, Dominik Spira, Ilja Demuth, Nathalie van der Velde, Lisette C. P. G. M. de Groot, Bruce M. Psaty, Michelle C. Odden, Alison E. Fohner, Claudia Langenberg, Nicholas J. Wareham, Stefania Bandinelli, Natasja M. van Schoor, Martijn Huisman, Qihua Tan, Joseph Zmuda, Dan Mellström, Magnus Karlsson, David A. Bennett, Aron S. Buchman, Philip L. De Jager, Andre G. Uitterlinden, Uwe Völker, Thomas Kocher, Alexander Teumer, Leocadio Rodriguéz-Mañas, Francisco J. García, José A. Carnicero, Pamela Herd, Lars Bertram, Claes Ohlsson, Joanne M. Murabito, David Melzer, George A. Kuchel, Luigi Ferrucci, David Karasik, Fernando Rivadeneira, Douglas P. Kiel, Luke C. Pilling
Publié dans Nature Communications (2021-01-01)