Bibliotecas PUC-SP - Busca Integrada

The Importance of Global Studies of the Genetics of Type 2 Diabetes

Por Mark I. McCarthy
Publicado no Diabetes & Metabolism Journal (2011-04-01)

The Importance of Context: Uncovering Species- and Tissue-Specific Effects of Genetic Risk Variants for Type 2 Diabetes

Por Soren Krogsgaard Thomsen, Mark I McCarthy, Mark I McCarthy, Mark I McCarthy, Anna L Gloyn, Anna L Gloyn, Anna L Gloyn
Publicado no Frontiers in Endocrinology (2016-08-01)

Clonal hematopoiesis is associated with reduced response to atezolizumab in non-small cell lung cancer

Por Ira Mellman, Minu Srivastava, Mark I McCarthy, Kipper Fletez-Brant, Christian Hammer, Barzin Nabet, Vylyny Chat
Publicado no Journal for ImmunoTherapy of Cancer (2025-09-01)

Evaluating the Performance of Fine-Mapping Strategies at Common Variant GWAS Loci.

Por Martijn van de Bunt, Adrian Cortes, IGAS Consortium, Matthew A Brown, Andrew P Morris, Mark I McCarthy
Publicado no PLoS Genetics (2015-01-01)

Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study.

Por Michael Wainberg, Anubha Mahajan, Anshul Kundaje, Mark I McCarthy, Erik Ingelsson, Nasa Sinnott-Armstrong, Manuel A Rivas
Publicado no PLoS Medicine (2019-12-01)

PLOS Genetics Data Sharing Policy: In Pursuit of Functional Utility.

Por Gregory S Barsh, Gregory M Cooper, Gregory P Copenhaver, Greg Gibson, Mark I McCarthy, Hua Tang, Scott M Williams
Publicado no PLoS Genetics (2015-12-01)

A Protein Domain and Family Based Approach to Rare Variant Association Analysis.

Por Tom G Richardson, Hashem A Shihab, Manuel A Rivas, Mark I McCarthy, Colin Campbell, Nicholas J Timpson, Tom R Gaunt
Publicado no PLoS ONE (2016-01-01)

Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes.

Por Delphine Fradin, Sophie Le Fur, Clémence Mille, Nadia Naoui, Chris Groves, Diana Zelenika, Mark I McCarthy, Mark Lathrop, Pierre Bougnères
Publicado no PLoS ONE (2012-01-01)

Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to type 2 diabetes.

Por Bahram Jafar-Mohammadi, Christopher J Groves, Katharine R Owen, Timothy M Frayling, Andrew T Hattersley, Mark I McCarthy, Anna L Gloyn
Publicado no PLoS ONE (2009-08-01)

Integration of biobank-scale genetics and plasma proteomics reveals evidence for causal processes in asthma risk and heterogeneity

Por Lauren J. Donoghue, Christian Benner, Diana Chang, Flaviyan Jerome Irudayanathan, Rion K. Pendergrass, Brian L. Yaspan, Anubha Mahajan, Mark I. McCarthy
Publicado no Cell Genomics (2025-05-01)

Genes Associated with Pancreas Development and Function Maintain Open Chromatin in iPSCs Generated from Human Pancreatic Beta Cells

Por Matthias Thurner, Liraz Shenhav, Agata Wesolowska-Andersen, Amanda J. Bennett, Amy Barrett, Anna L. Gloyn, Mark I. McCarthy, Nicola L. Beer, Shimon Efrat
Publicado no Stem Cell Reports (2017-11-01)

Deep learning models predict regulatory variants in pancreatic islets and refine type 2 diabetes association signals

Por Agata Wesolowska-Andersen, Grace Zhuo Yu, Vibe Nylander, Fernando Abaitua, Matthias Thurner, Jason M Torres, Anubha Mahajan, Anna L Gloyn, Mark I McCarthy
Publicado no eLife (2020-01-01)

Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells [version 2; peer review: 2 approved]

Por Jason M. Torres, Vibe Nylander, Han Sun, Martijn van de Bunt, Damien J. Downes, Mark I. McCarthy, Jim R. Hughes, Anna L. Gloyn
Publicado no Wellcome Open Research (2023-08-01)

Metabolic profiling in Maturity-onset diabetes of the young (MODY) and young onset type 2 diabetes fails to detect robust urinary biomarkers.

Por Anna L Gloyn, Johan H Faber, Daniel Malmodin, Gaya Thanabalasingham, Francis Lam, Per Magne Ueland, Mark I McCarthy, Katharine R Owen, Dorrit Baunsgaard
Publicado no PLoS ONE (2012-01-01)

Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy

Por Zia Khan, Min Jung, Megan Crow, Rajat Mohindra, Vidya Maiya, Joshua S. Kaminker, David H. Hackos, G. Scott Chandler, Mark I. McCarthy, Tushar Bhangale
Publicado no Genome Medicine (2023-06-01)

Burden of Diabetes and First Evidence for the Utility of HbA1c for Diagnosis and Detection of Diabetes in Urban Black South Africans: The Durban Diabetes Study.

Por Thomas R Hird, Fraser J Pirie, Tonya M Esterhuizen, Brian O'Leary, Mark I McCarthy, Elizabeth H Young, Manjinder S Sandhu, Ayesha A Motala
Publicado no PLoS ONE (2016-01-01)

Developing a network view of type 2 diabetes risk pathways through integration of genetic, genomic and functional data

Por Juan Fernández-Tajes, Kyle J. Gaulton, Martijn van de Bunt, Jason Torres, Matthias Thurner, Anubha Mahajan, Anna L. Gloyn, Kasper Lage, Mark I. McCarthy
Publicado no Genome Medicine (2019-03-01)

Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery.

Por Reedik Mägi, Sean Manning, Ahmed Yousseif, Andrea Pucci, Ferruccio Santini, Efthimia Karra, Giorgia Querci, Caterina Pelosini, Mark I McCarthy, Cecilia M Lindgren, Rachel L Batterham
Publicado no PLoS ONE (2013-01-01)

Exploring the developmental overnutrition hypothesis using parental-offspring associations and FTO as an instrumental variable.

Por Debbie A Lawlor, Nicholas J Timpson, Roger M Harbord, Sam Leary, Andy Ness, Mark I McCarthy, Timothy M Frayling, Andrew T Hattersley, George Davey Smith
Publicado no PLoS Medicine (2008-03-01)

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.

Por Martijn van de Bunt, Kyle J Gaulton, Leopold Parts, Ignasi Moran, Paul R Johnson, Cecilia M Lindgren, Jorge Ferrer, Anna L Gloyn, Mark I McCarthy
Publicado no PLoS ONE (2013-01-01)