Bibliotecas PUC-SP - Busca Integrada

Editorial: Can population health be personalized? Estonia and Finland as examples

por Helena Kääriäinen, Andres Metspalu, Markus Perola, Markus Perola
Publicado en Frontiers in Genetics (2022-10-01)

Psychosocial Effects of Receiving Genome-Wide Polygenic Risk Information Concerning Type 2 Diabetes and Coronary Heart Disease: A Randomized Controlled Trial

por Otto Halmesvaara, Marleena Vornanen, Marleena Vornanen, Marleena Vornanen, Helena Kääriäinen, Markus Perola, Markus Perola, Kati Kristiansson, Kati Kristiansson, Hanna Konttinen
Publicado en Frontiers in Genetics (2022-05-01)

Economic evaluation of using polygenic risk score to guide risk screening and interventions for the prevention of type 2 diabetes in individuals with high overall baseline risk

por Janne Martikainen, Aku-Ville Lehtimäki, Kari Jalkanen, Piia Lavikainen, Teemu Paajanen, Teemu Paajanen, Heidi Marjonen, Heidi Marjonen, Kati Kristiansson, Kati Kristiansson, Jaana Lindström, Markus Perola, Markus Perola
Publicado en Frontiers in Genetics (2022-09-01)

The Detection of Metabolite-Mediated Gene Module Co-Expression Using Multivariate Linear Models.

por Trishanta Padayachee, Tatsiana Khamiakova, Ziv Shkedy, Markus Perola, Perttu Salo, Tomasz Burzykowski
Publicado en PLoS ONE (2016-01-01)

Bayesian variable selection in searching for additive and dominant effects in genome-wide data.

por Tomi Peltola, Pekka Marttinen, Antti Jula, Veikko Salomaa, Markus Perola, Aki Vehtari
Publicado en PLoS ONE (2012-01-01)

Mendelian randomisation analysis of clustered causal effects of body mass on cardiometabolic biomarkers

por Susana Conde, Xiaoguang Xu, Hui Guo, Markus Perola, Teresa Fazia, Luisa Bernardinelli, Carlo Berzuini
Publicado en BMC Bioinformatics (2018-07-01)

Reaching for Precision Healthcare in Finland via Use of Genomic Data

por Tiina Wahlfors, Birgit Simell, Kati Kristiansson, Sirpa Soini, Terhi Kilpi, Marina Erhola, Markus Perola
Publicado en Frontiers in Genetics (2022-04-01)

ALT levels, alcohol use, and metabolic risk factors have prognostic relevance for liver-related outcomes in the general population

por Ville Männistö, Veikko Salomaa, Antti Jula, Annamari Lundqvist, Satu Männistö, Markus Perola, Fredrik Åberg
Publicado en JHEP Reports (2024-10-01)

Combined effects of thrombosis pathway gene variants predict cardiovascular events.

por Kirsi Auro, Mervi Alanne, Kati Kristiansson, Kaisa Silander, Kari Kuulasmaa, Veikko Salomaa, Leena Peltonen, Markus Perola
Publicado en PLoS Genetics (2007-07-01)

Waist-hip ratio is superior to BMI in predicting liver-related outcomes and synergizes with harmful alcohol use

por Fredrik Åberg, Martti Färkkilä, Veikko Salomaa, Antti Jula, Satu Männistö, Markus Perola, Annamari Lundqvist, Ville Männistö
Publicado en Communications Medicine (2023-09-01)

Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches

por Gordan Lauc, Markus Perola, Domagoj Kifer, Olga Gornik, Massimo Mangino, Ana Cvetko, Marko Tijardović, Toma Keser
Publicado en BMJ Open Diabetes Research & Care (2021-03-01)

Divergent trends in the incidence and mortality of acute myocardial ischaemic syndrome, especially in women. Evidence from Finland in 1996–2021

por Atte Kallström, Ida Holopainen, Oleg Kambur, Markus Perola, Veikko Salomaa, Aki S. Havulinna, Markus Ramste, Juha Sinisalo
Publicado en Annals of Medicine (2024-12-01)

Schizophrenia genetic risk and labour market outcomes in the Finnish general population: Are schizophrenia-related traits penalised or rewarded?

por Aaro Hazak, Johanna Liuhanen, Katri Kantojärvi, Sonja Sulkava, Tuija Jääskeläinen, Veikko Salomaa, Seppo Koskinen, Markus Perola, Tiina Paunio
Publicado en Comprehensive Psychiatry (2025-07-01)

Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design

por Marja-Liisa Nuotio, Heini Sánez Tähtisalo, Alexandra Lahtinen, Kati Donner, Frej Fyhrquist, Markus Perola, Kimmo K Kontula, Timo P Hiltunen
Publicado en Epigenetics (2022-11-01)

Serum lipopolysaccharides predict advanced liver disease in the general population

por Ville Männistö, Martti Färkkilä, Pirkko Pussinen, Antti Jula, Satu Männistö, Annamari Lundqvist, Liisa Valsta, Veikko Salomaa, Markus Perola, Fredrik Åberg
Publicado en JHEP Reports (2019-11-01)

Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome.

por Olavi Parkkonen, Mikko T Nieminen, Paula Vesterinen, Taina Tervahartiala, Markus Perola, Veikko Salomaa, Pekka Jousilahti, Timo Sorsa, Pirkko J Pussinen, Juha Sinisalo
Publicado en PLoS ONE (2017-01-01)

Insulin Resistance and Genetic Risk Predict Liver‐Related Outcomes and Death in Nonalcoholic Fatty Liver Disease

por Christopher J. Danford, Z. Gordon Jiang, Veikko Salomaa, Martti Färkkilä, Antti Jula, Satu Männistö, Annamari Lundqvist, Liisa Valsta, Markus Perola, Fredrik Åberg
Publicado en Hepatology Communications (2019-12-01)

Metabolic Biomarker Discovery for Risk of Peripheral Artery Disease Compared With Coronary Artery Disease: Lipoprotein and Metabolite Profiling of 31 657 Individuals From 5 Prospec...

por Emmi Tikkanen, Vilma Jägerroos, Michael V. Holmes, Naveed Sattar, Mika Ala‐Korpela, Pekka Jousilahti, Annamari Lundqvist, Markus Perola, Veikko Salomaa, Peter Würtz
Publicado en Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2021-12-01)

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies.

por Toomas Haller, Liis Leitsalu, Krista Fischer, Marja-Liisa Nuotio, Tõnu Esko, Dorothea Irene Boomsma, Kirsten Ohm Kyvik, Tim D Spector, Markus Perola, Andres Metspalu
Publicado en PLoS ONE (2017-01-01)

Changes in the fine-scale genetic structure of Finland through the 20th century.

por Sini Kerminen, Nicola Cerioli, Darius Pacauskas, Aki S Havulinna, Markus Perola, Pekka Jousilahti, Veikko Salomaa, Mark J Daly, Rupesh Vyas, Samuli Ripatti, Matti Pirinen
Publicado en PLoS Genetics (2021-03-01)