Bibliotecas PUC-SP - Busca Integrada

Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis.

gan Thomas LaFramboise, Ninad Dewal, Katherine Wilkins, Itsik Pe'er, Matthew L Freedman
Cyhoeddwyd yn PLoS Genetics (2010-09-01)

ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer

gan Shaghayegh Nouruzi, Dwaipayan Ganguli, Nakisa Tabrizian, Maxim Kobelev, Olena Sivak, Takeshi Namekawa, Daksh Thaper, Sylvan C. Baca, Matthew L. Freedman, Adeleke Aguda, Alastair Davies, Amina Zoubeidi
Cyhoeddwyd yn Nature Communications (2022-04-01)

The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancer

gan Alexandros Armaos, François Serra, Iker Núñez-Carpintero, Ji-Heui Seo, Sylvan C. Baca, Stefano Gustincich, Alfonso Valencia, Matthew L. Freedman, Davide Cirillo, Claudia Giambartolomei, Gian Gaetano Tartaglia
Cyhoeddwyd yn Nature Communications (2023-12-01)

Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription

gan Umut Berkay Altıntaş, Ji-Heui Seo, Claudia Giambartolomei, Dogancan Ozturan, Brad J. Fortunato, Geoffrey M. Nelson, Seth R. Goldman, Karen Adelman, Faraz Hach, Matthew L. Freedman, Nathan A. Lack
Cyhoeddwyd yn Nature Communications (2024-11-01)

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases

gan Tesa M. Severson, Yanyun Zhu, Angelo M. De Marzo, Tracy Jones, Jonathan W. Simons, William G. Nelson, Srinivasan Yegnasubramanian, Matthew L. Freedman, Lodewyk Wessels, Andries M. Bergman, Michael C. Haffner, Wilbert Zwart
Cyhoeddwyd yn Molecular Oncology (2021-07-01)

A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer

gan Kaivalya Walavalkar, Bharath Saravanan, Anurag Kumar Singh, Ranveer Singh Jayani, Ashwin Nair, Umer Farooq, Zubairul Islam, Deepanshu Soota, Rajat Mann, Padubidri V. Shivaprasad, Matthew L. Freedman, Radhakrishnan Sabarinathan, Christopher A. Haiman, Dimple Notani
Cyhoeddwyd yn Nature Communications (2020-07-01)

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer

gan Neel Shah, Ping Wang, John Wongvipat, Wouter R Karthaus, Wassim Abida, Joshua Armenia, Shira Rockowitz, Yotam Drier, Bradley E Bernstein, Henry W Long, Matthew L Freedman, Vivek K Arora, Deyou Zheng, Charles L Sawyers
Cyhoeddwyd yn eLife (2017-09-01)

Androgen receptor and MYC equilibration centralizes on developmental super-enhancer

gan Haiyang Guo, Yiming Wu, Mannan Nouri, Sandor Spisak, Joshua W. Russo, Adam G. Sowalsky, Mark M. Pomerantz, Zhao Wei, Keegan Korthauer, Ji-Heui Seo, Liyang Wang, Seiji Arai, Matthew L. Freedman, Housheng Hansen He, Shaoyong Chen, Steven P. Balk
Cyhoeddwyd yn Nature Communications (2021-12-01)

Super-Enhancer-Associated LncRNA UCA1 Interacts Directly with AMOT to Activate YAP Target Genes in Epithelial Ovarian Cancer

gan Xianzhi Lin, Tassja J. Spindler, Marcos Abraão de Souza Fonseca, Rosario I. Corona, Ji-Heui Seo, Felipe Segato Dezem, Lewyn Li, Janet M. Lee, Henry W. Long, Thomas A. Sellers, Beth Y. Karlan, Houtan Noushmehr, Matthew L. Freedman, Simon A. Gayther, Kate Lawrenson
Cyhoeddwyd yn iScience (2019-07-01)

Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer

gan Rosario I. Corona, Ji-Heui Seo, Xianzhi Lin, Dennis J. Hazelett, Jessica Reddy, Marcos A. S. Fonseca, Forough Abassi, Yvonne G. Lin, Paulette Y. Mhawech-Fauceglia, Sohrab P. Shah, David G. Huntsman, Alexander Gusev, Beth Y. Karlan, Benjamin P. Berman, Matthew L. Freedman, Simon A. Gayther, Kate Lawrenson
Cyhoeddwyd yn Nature Communications (2020-04-01)

Patterns of structural variation define prostate cancer across disease states

gan Meng Zhou, Minjeong Ko, Anna C.H. Hoge, Kelsey Luu, Yuzhen Liu, Magdalena L. Russell, William W. Hannon, Zhenwei Zhang, Jian Carrot-Zhang, Rameen Beroukhim, Eliezer M. Van Allen, Atish D. Choudhury, Peter S. Nelson, Matthew L. Freedman, Mary-Ellen Taplin, Matthew Meyerson, Srinivas R. Viswanathan, Gavin Ha
Cyhoeddwyd yn JCI Insight (2022-09-01)

Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer

gan Larysa Poluben, Mannan Nouri, Jiaqian Liang, Shaoyong Chen, Andreas Varkaris, Betul Ersoy-Fazlioglu, Olga Voznesensky, Irene I. Lee, Xintao Qiu, Laura Cato, Ji-Heui Seo, Matthew L. Freedman, Adam G. Sowalsky, Nathan A. Lack, Eva Corey, Peter S. Nelson, Myles Brown, Henry W. Long, Joshua W. Russo, Steven P. Balk
Cyhoeddwyd yn Cell Reports (2025-01-01)

Trans-ethnic variation in germline variants of patients with renal cell carcinoma

gan Sarah Abou Alaiwi, Amin H. Nassar, Elio Adib, Stefan M. Groha, Elie W. Akl, Bradley A. McGregor, Edward D. Esplin, Shan Yang, Kathryn Hatchell, Vincent Fusaro, Sarah Nielsen, David J. Kwiatkowski, Guru P. Sonpavde, Mark Pomerantz, Judy E. Garber, Matthew L. Freedman, Huma Q. Rana, Alexander Gusev, Toni K. Choueiri
Cyhoeddwyd yn Cell Reports (2021-03-01)

Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome

gan Xintao Qiu, Lisha G. Brown, Jennifer L. Conner, Holly M. Nguyen, Nadia Boufaied, Sarah Abou Alaiwi, Ji-Heui Seo, Talal El Zarif, Connor Bell, Edward O’Connor, Brian Hanratty, Mark Pomerantz, Matthew L. Freedman, Myles Brown, Michael C. Haffner, Peter S. Nelson, Felix Y. Feng, David P. Labbé, Henry W. Long, Eva Corey
Cyhoeddwyd yn JCI Insight (2022-05-01)

Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis.

gan Mark M Pomerantz, Yashaswi Shrestha, Richard J Flavin, Meredith M Regan, Kathryn L Penney, Lorelei A Mucci, Meir J Stampfer, David J Hunter, Stephen J Chanock, Eric J Schafer, Jennifer A Chan, Josep Tabernero, José Baselga, Andrea L Richardson, Massimo Loda, William K Oh, Philip W Kantoff, William C Hahn, Matthew L Freedman
Cyhoeddwyd yn PLoS Genetics (2010-11-01)

A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus

gan Sandor Spisak, Viktoria Tisza, Pier Vitale Nuzzo, Ji-Heui Seo, Balint Pataki, Dezso Ribli, Zsofia Sztupinszki, Connor Bell, Mersedeh Rohanizadegan, David R. Stillman, Sarah Abou Alaiwi, Alan H. Bartels, Marton Papp, Anamay Shetty, Forough Abbasi, Xianzhi Lin, Kate Lawrenson, Simon A. Gayther, Mark Pomerantz, Sylvan Baca, Norbert Solymosi, Istvan Csabai, Zoltan Szallasi, Alexander Gusev, Matthew L. Freedman
Cyhoeddwyd yn Nature Communications (2023-08-01)

CREB5 reprograms FOXA1 nuclear interactions to promote resistance to androgen receptor-targeting therapies

gan Justin H Hwang, Rand Arafeh, Ji-Heui Seo, Sylvan C Baca, Megan Ludwig, Taylor E Arnoff, Lydia Sawyer, Camden Richter, Sydney Tape, Hannah E Bergom, Sean McSweeney, Jonathan P Rennhack, Sarah A Klingenberg, Alexander TM Cheung, Jason Kwon, Jonathan So, Steven Kregel, Eliezer M Van Allen, Justin M Drake, Matthew L Freedman, William C Hahn
Cyhoeddwyd yn eLife (2022-05-01)

Author Correction: A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locus

gan Sandor Spisak, Viktoria Tisza, Pier Vitale Nuzzo, Ji-Heui Seo, Balint Pataki, Dezso Ribli, Zsofia Sztupinszki, Connor Bell, Mersedeh Rohanizadegan, David R. Stillman, Sarah Abou Alaiwi, Alan H. Bartels, Marton Papp, Anamay Shetty, Forough Abbasi, Xianzhi Lin, Kate Lawrenson, Simon A. Gayther, Mark Pomerantz, Sylvan Baca, Norbert Solymosi, Istvan Csabai, Zoltan Szallasi, Alexander Gusev, Matthew L. Freedman
Cyhoeddwyd yn Nature Communications (2023-10-01)

A Study of High-Grade Serous Ovarian Cancer Origins Implicates the SOX18 Transcription Factor in Tumor Development

gan Kate Lawrenson, Marcos A.S. Fonseca, Annie Y. Liu, Felipe Segato Dezem, Janet M. Lee, Xianzhi Lin, Rosario I. Corona, Forough Abbasi, Kevin C. Vavra, Huy Q. Dinh, Navjot Kaur Gill, Ji-Heui Seo, Simon Coetzee, Yvonne G. Lin, Tanja Pejovic, Paulette Mhawech-Fauceglia, Amy C. Rowat, Ronny Drapkin, Beth Y. Karlan, Dennis J. Hazelett, Matthew L. Freedman, Simon A. Gayther, Houtan Noushmehr
Cyhoeddwyd yn Cell Reports (2019-12-01)

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential

gan Jeroen Kneppers, Tesa M. Severson, Joseph C. Siefert, Pieter Schol, Stacey E. P. Joosten, Ivan Pak Lok Yu, Chia-Chi Flora Huang, Tunç Morova, Umut Berkay Altıntaş, Claudia Giambartolomei, Ji-Heui Seo, Sylvan C. Baca, Isa Carneiro, Eldon Emberly, Bogdan Pasaniuc, Carmen Jerónimo, Rui Henrique, Matthew L. Freedman, Lodewyk F. A. Wessels, Nathan A. Lack, Andries M. Bergman, Wilbert Zwart
Cyhoeddwyd yn Nature Communications (2022-11-01)