Bibliotecas PUC-SP - Busca Integrada

APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions

Por Marat D. Kazanov, Steven A. Roberts, Paz Polak, John Stamatoyannopoulos, Leszek J. Klimczak, Dmitry A. Gordenin, Shamil R. Sunyaev
Publicado no Cell Reports (2015-11-01)

The Great Majority of Homologous Recombination Repair-Deficient Tumors Are Accounted for by Established Causes

Por Paula Štancl, Nancy Hamel, Keith M. Sigel, William D. Foulkes, William D. Foulkes, William D. Foulkes, Rosa Karlić, Paz Polak
Publicado no Frontiers in Genetics (2022-06-01)

COOBoostR: An Extreme Gradient Boosting-Based Tool for Robust Tissue or Cell-of-Origin Prediction of Tumors

Por Sungmin Yang, Kyungsik Ha, Woojeung Song, Masashi Fujita, Kirsten Kübler, Paz Polak, Eiso Hiyama, Hidewaki Nakagawa, Hong-Gee Kim, Hwajin Lee
Publicado no Life (2022-12-01)

Learning the cellular origins across cancers using single-cell chromatin landscapes

Por Mohamad D. Bairakdar, Wooseung Lee, Bruno Giotti, Akhil Kumar, Paula Stancl, Elvin Wagenblast, Dolores Hambardzumyan, Paz Polak, Rosa Karlic, Alexander M. Tsankov
Publicado no Nature Communications (2025-09-01)

Somatic mutation landscape reveals differential variability of cell-of-origin for primary liver cancer

Por Kyungsik Ha, Masashi Fujita, Rosa Karlić, Sungmin Yang, Ruidong Xue, Chong Zhang, Fan Bai, Ning Zhang, Yujin Hoshida, Paz Polak, Hidewaki Nakagawa, Hong-Gee Kim, Hwajin Lee
Publicado no Heliyon (2020-02-01)

Current gene panels account for nearly all homologous recombination repair-associated multiple-case breast cancer families

Por Thibaut S. Matis, Nadia Zayed, Bouchra Labraki, Manon de Ladurantaye, Théophane A. Matis, José Camacho Valenzuela, Nancy Hamel, Adrienne Atayan, Barbara Rivera, Yuval Tabach, Patricia N. Tonin, Alexandre Orthwein, Anne-Marie Mes-Masson, Zaki El Haffaf, William D. Foulkes, Paz Polak
Publicado no npj Breast Cancer (2021-08-01)

Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Por Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid D. Morris, Lincoln D. Stein, PCAWG Consortium
Publicado no Nature Communications (2022-12-01)

A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns

Por Wei Jiao, Gurnit Atwal, Paz Polak, Rosa Karlic, Edwin Cuppen, PCAWG Tumor Subtypes and Clinical Translation Working Group, Alexandra Danyi, Jeroen de Ridder, Carla van Herpen, Martijn P. Lolkema, Neeltje Steeghs, Gad Getz, Quaid Morris, Lincoln D. Stein, PCAWG Consortium
Publicado no Nature Communications (2020-02-01)

Characterization of genetic predisposition to molecular subtypes of breast cancer in Brazilian patients

Por Daniele Paixão, Giovana Tardin Torrezan, Giovana Tardin Torrezan, Karina Miranda Santiago, Maria Nirvana Formiga, Samuel Terkper Ahuno, Emmanuel Dias-Neto, Emmanuel Dias-Neto, Israel Tojal da Silva, Israel Tojal da Silva, William D. Foulkes, Paz Polak, Dirce Maria Carraro, Dirce Maria Carraro
Publicado no Frontiers in Oncology (2022-08-01)

A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA

Por Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publicado no Nature Communications (2022-12-01)

Author Correction: A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA

Por Anna-Lisa Doebley, Minjeong Ko, Hanna Liao, A. Eden Cruikshank, Katheryn Santos, Caroline Kikawa, Joseph B. Hiatt, Robert D. Patton, Navonil De Sarkar, Katharine A. Collier, Anna C. H. Hoge, Katharine Chen, Anat Zimmer, Zachary T. Weber, Mohamed Adil, Jonathan B. Reichel, Paz Polak, Viktor A. Adalsteinsson, Peter S. Nelson, David MacPherson, Heather A. Parsons, Daniel G. Stover, Gavin Ha
Publicado no Nature Communications (2023-01-01)

Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa

Por Samuel Terkper Ahuno, Anna-Lisa Doebley, Thomas U. Ahearn, Joel Yarney, Nicholas Titiloye, Nancy Hamel, Ernest Adjei, Joe-Nat Clegg-Lamptey, Lawrence Edusei, Baffour Awuah, Xiaoyu Song, Verna Vanderpuye, Mustapha Abubakar, Maire Duggan, Daniel G. Stover, Kofi Nyarko, John M. S. Bartlett, Francis Aitpillah, Daniel Ansong, Kevin L. Gardner, Felix Andy Boateng, Anne M. Bowcock, Carlos Caldas, William D. Foulkes, Seth Wiafe, Beatrice Wiafe-Addai, Montserrat Garcia-Closas, Alexander Kwarteng, Gavin Ha, Jonine D. Figueroa, Paz Polak, the Ghana Breast Health Study Team
Publicado no npj Precision Oncology (2021-09-01)

Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

Por Viktor A. Adalsteinsson, Gavin Ha, Samuel S. Freeman, Atish D. Choudhury, Daniel G. Stover, Heather A. Parsons, Gregory Gydush, Sarah C. Reed, Denisse Rotem, Justin Rhoades, Denis Loginov, Dimitri Livitz, Daniel Rosebrock, Ignaty Leshchiner, Jaegil Kim, Chip Stewart, Mara Rosenberg, Joshua M. Francis, Cheng-Zhong Zhang, Ofir Cohen, Coyin Oh, Huiming Ding, Paz Polak, Max Lloyd, Sairah Mahmud, Karla Helvie, Margaret S. Merrill, Rebecca A. Santiago, Edward P. O’Connor, Seong H. Jeong, Rachel Leeson, Rachel M. Barry, Joseph F. Kramkowski, Zhenwei Zhang, Laura Polacek, Jens G. Lohr, Molly Schleicher, Emily Lipscomb, Andrea Saltzman, Nelly M. Oliver, Lori Marini, Adrienne G. Waks, Lauren C. Harshman, Sara M. Tolaney, Eliezer M. Van Allen, Eric P. Winer, Nancy U. Lin, Mari Nakabayashi, Mary-Ellen Taplin, Cory M. Johannessen, Levi A. Garraway, Todd R. Golub, Jesse S. Boehm, Nikhil Wagle, Gad Getz, J. Christopher Love, Matthew Meyerson
Publicado no Nature Communications (2017-11-01)