Bibliotecas PUC-SP - Busca Integrada

The cytotoxic action of BCI is not dependent on its stated DUSP1 or DUSP6 targets in neuroblastoma cells

por Elliott M. Thompson, Vruti Patel, Vinothini Rajeeve, Pedro R Cutillas, Andrew W. Stoker
Publicado no FEBS Open Bio (2022-07-01)

Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases

por David Bradley, Cristina Viéitez, Vinothini Rajeeve, Joel Selkrig, Pedro R. Cutillas, Pedro Beltrao
Publicado no Cell Reports (2021-01-01)

HMMR has oncoprotein-like properties in neuroblastoma cells and high HMMR expression has independent prognostic potential in neuroblastomas

por Christina Karapouliou, Elisyazaviera M. Faizul, Vinothini Rajeeve, Pedro R. Cutillas, Andrew W. Stoker
Publicado no Scientific Reports (2025-11-01)

Community detection in empirical kinase networks identifies new potential members of signalling pathways.

por Celia De Los Angeles Colomina Basanta, Marya Bazzi, Maruan Hijazi, Conrad Bessant, Pedro R Cutillas
Publicado no PLoS Computational Biology (2023-06-01)

In Silico Analysis Predicts Nuclear Factors NR2F6 and YAP1 as Mesenchymal Subtype-Specific Therapeutic Targets for Ovarian Cancer Patients

por Wanja Kassuhn, Pedro R. Cutillas, Mirjana Kessler, Jalid Sehouli, Elena I. Braicu, Nils Blüthgen, Hagen Kulbe
Publicado no Cancers (2023-06-01)

Microtubule-associated proteins MAP7 and MAP7D1 promote DNA double-strand break repair in the G1 cell cycle phase

por Arlinda Dullovi, Meryem Ozgencil, Vinothini Rajvee, Wai Yiu Tse, Pedro R. Cutillas, Sarah A. Martin, Zuzana Hořejší
Publicado no iScience (2023-03-01)

Exactly defined molecular weight poly(ethylene glycol) allows for facile identification of PEGylation sites on proteins

por Maria J. Burggraef, Adam Oxley, Naveed A. Zaidi, Pedro R. Cutillas, Piers R. J. Gaffney, Andrew G. Livingston
Publicado no Nature Communications (2024-11-01)

Shedding of bevacizumab in tumour cells-derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma

por Thomas Simon, Sotiria Pinioti, Pascale Schellenberger, Vinothini Rajeeve, Franz Wendler, Pedro R. Cutillas, Alice King, Justin Stebbing, Georgios Giamas
Publicado no Molecular Cancer (2018-08-01)

Phosphoproteomics identifies determinants of PAK inhibitor sensitivity in leukaemia cells

por Pedro Casado, Santiago Marfa, Marym M. Hadi, Henry Gerdes, Sandra M. Martin-Guerrero, Farideh Miraki-Moud, Vinothini Rajeeve, Pedro R. Cutillas
Publicado no Cell Communication and Signaling (2025-03-01)

Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs

por Henry Gerdes, Pedro Casado, Arran Dokal, Maruan Hijazi, Nosheen Akhtar, Ruth Osuntola, Vinothini Rajeeve, Jude Fitzgibbon, Jon Travers, David Britton, Shirin Khorsandi, Pedro R. Cutillas
Publicado no Nature Communications (2021-03-01)

HDAC Inhibition Restores Response to HER2-Targeted Therapy in Breast Cancer via <i>PHLDA1</i> Induction

por Natasha S. Clayton, Edward P. Carter, Abbie E. Fearon, James A. Heward, Lucía Rodríguez Fernández, Lina Boughetane, Edmund H. Wilkes, Pedro R. Cutillas, Richard P. Grose
Publicado no International Journal of Molecular Sciences (2023-03-01)

Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modelling

por Wasfi Alrawashdeh, Richard Jones, Laurent Dumartin, Tomasz P. Radon, Pedro R. Cutillas, Roger M. Feakins, Branko Dmitrovic, Ihsan Ekin Demir, Guralp O. Ceyhan, Tatjana Crnogorac‐Jurcevic
Publicado no Molecular Oncology (2019-05-01)

NCK Associated Protein 1 Modulated by miRNA‐214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia

por Tayyab Adeel Afzal, Le Anh Luong, Dan Chen, Cheng Zhang, Feng Yang, Qishan Chen, Weiwei An, Edmund Wilkes, Kenta Yashiro, Pedro R. Cutillas, Li Zhang, Qingzhong Xiao
Publicado no Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2016-12-01)

The CKS1/CKS2 Proteostasis Axis Is Crucial to Maintain Hematopoietic Stem Cell Function

por William Grey, Samantha Atkinson, Beatrice Rix, Pedro Casado, Linda Ariza-McNaughton, Cathy Hawley, Miriam L. Sopoena, Katherine S. Bridge, David Kent, Pedro R. Cutillas, Dominique Bonnet
Publicado no HemaSphere (2023-03-01)

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1

por Jale Yuzugulen, Julie A. Douthwaite, Elizabeth G. Wood, Inmaculada C. Villar, Nimesh S. A. Patel, James Jegard, Hubert Gaertner, Irène Rossitto-Borlat, Keith Rose, Oliver Hartley, Pedro R. Cutillas, Amrita Ahluwalia, Roger Corder
Publicado no Scientific Reports (2017-07-01)

Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes

por Kathryn Davidson, Paul Grevitt, Maria F. Contreras-Gerenas, Katherine S. Bridge, Miguel Hermida, Kunal M. Shah, Faraz K. Mardakheh, Mark Stubbs, Rosemary Burke, Pedro Casado, Pedro R. Cutillas, Sarah A. Martin, Tyson V. Sharp
Publicado no Cell Death and Disease (2021-11-01)

The MAP kinase pathway coordinates crossover designation with disassembly of synaptonemal complex proteins during meiosis

por Saravanapriah Nadarajan, Firaz Mohideen, Yonatan B Tzur, Nuria Ferrandiz, Oliver Crawley, Alex Montoya, Peter Faull, Ambrosius P Snijders, Pedro R Cutillas, Ashwini Jambhekar, Michael D Blower, Enrique Martinez-Perez, J Wade Harper, Monica P Colaiacovo
Publicado no eLife (2016-02-01)

Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes

por Pedro Casado, Ana Rio-Machin, Juho J. Miettinen, Findlay Bewicke-Copley, Kevin Rouault-Pierre, Szilvia Krizsan, Alun Parsons, Vinothini Rajeeve, Farideh Miraki-Moud, David C. Taussig, Csaba Bödör, John Gribben, Caroline Heckman, Jude Fitzgibbon, Pedro R. Cutillas
Publicado no Signal Transduction and Targeted Therapy (2023-02-01)

A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease

por Sarah E. Conduit, Wayne Pearce, Amandeep Bhamra, Benoit Bilanges, Laura Bozal-Basterra, Lazaros C. Foukas, Mathias Cobbaut, Sandra D. Castillo, Mohammad Amin Danesh, Mahreen Adil, Arkaitz Carracedo, Mariona Graupera, Neil Q. McDonald, Peter J. Parker, Pedro R. Cutillas, Silvia Surinova, Bart Vanhaesebroeck
Publicado no Nature Communications (2024-08-01)

Endothelial cell rearrangements during vascular patterning require PI3-kinase-mediated inhibition of actomyosin contractility

por Ana Angulo-Urarte, Pedro Casado, Sandra D. Castillo, Piotr Kobialka, Maria Paraskevi Kotini, Ana M. Figueiredo, Pau Castel, Vinothini Rajeeve, Maria Milà-Guasch, Jaime Millan, Cora Wiesner, Helena Serra, Laia Muixi, Oriol Casanovas, Francesc Viñals, Markus Affolter, Holger Gerhardt, Stephan Huveneers, Heinz-Georg Belting, Pedro R. Cutillas, Mariona Graupera
Publicado no Nature Communications (2018-11-01)