Bibliotecas PUC-SP - Busca Integrada

A global view of the aspiring physician-scientist

von Christopher S Williams, W Kimryn Rathmell, John M Carethers, Diane M Harper, YM Dennis Lo, Peter J Ratcliffe, Mone Zaidi
Veröffentlicht in eLife (2022-09-01)

N-terminal cysteine acetylation and oxidation patterns may define protein stability

von Karen C. Heathcote, Thomas P. Keeley, Matti Myllykoski, Malin Lundekvam, Nina McTiernan, Salma Akter, Norma Masson, Peter J. Ratcliffe, Thomas Arnesen, Emily Flashman
Veröffentlicht in Nature Communications (2024-06-01)

HIFα isoform specific activities drive cell-type specificity of VHL-associated oncogenesis

von Joanna D.C.C. Lima, Madeleine Hooker, Ran Li, Ayslan B. Barros, Norma Masson, Christopher W. Pugh, David R. Mole, Julie Adam, Peter J. Ratcliffe, Samvid Kurlekar
Veröffentlicht in Nature Communications (2025-10-01)

Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations

von Carme Camps, Nayia Petousi, Celeste Bento, Holger Cario, Richard R. Copley, Mary Frances McMullin, Richard van Wijk, Peter J. Ratcliffe, Peter A. Robbins, Jenny C. Taylor
Veröffentlicht in Haematologica (2016-11-01)

Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway.

von Steffen Grampp, Virginia Schmid, Rafik Salama, Victoria Lauer, Franziska Kranz, James L Platt, James Smythies, Hani Choudhry, Margarete Goppelt-Struebe, Peter J Ratcliffe, David R Mole, Johannes Schödel
Veröffentlicht in PLoS Genetics (2017-07-01)

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

von Matthew E Cockman, Kerstin Lippl, Ya-Min Tian, Hamish B Pegg, William D Figg Jnr, Martine I Abboud, Raphael Heilig, Roman Fischer, Johanna Myllyharju, Christopher J Schofield, Peter J Ratcliffe
Veröffentlicht in eLife (2019-09-01)

Hif-2α programs oxygen chemosensitivity in chromaffin cells

von Maria Prange-Barczynska, Holly A. Jones, Yoichiro Sugimoto, Xiaotong Cheng, Joanna D.C.C. Lima, Indrika Ratnayaka, Gillian Douglas, Keith J. Buckler, Peter J. Ratcliffe, Thomas P. Keeley, Tammie Bishop
Veröffentlicht in The Journal of Clinical Investigation (2024-09-01)

Genetic variation at the 8q24.21 renal cancer susceptibility locus affects HIF binding to a MYC enhancer

von Steffen Grampp, James L. Platt, Victoria Lauer, Rafik Salama, Franziska Kranz, Viviana K. Neumann, Sven Wach, Christine Stöhr, Arndt Hartmann, Kai-Uwe Eckardt, Peter J. Ratcliffe, David R. Mole, Johannes Schödel
Veröffentlicht in Nature Communications (2016-10-01)

Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α).

von Armin Thalhammer, Zuzana Bencokova, Rachel Poole, Christoph Loenarz, Julie Adam, Linda O'Flaherty, Johannes Schödel, David Mole, Konstantinos Giaslakiotis, Christopher J Schofield, Ester M Hammond, Peter J Ratcliffe, Patrick J Pollard
Veröffentlicht in PLoS ONE (2011-01-01)

Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans.

von Tammie Bishop, Kah Weng Lau, Andrew C R Epstein, Stuart K Kim, Min Jiang, Delia O'Rourke, Christopher W Pugh, Jonathan M Gleadle, Martin S Taylor, Jonathan Hodgkin, Peter J Ratcliffe
Veröffentlicht in PLoS Biology (2004-10-01)

Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation

von Matthew C. Frise, David A. Holdsworth, Andrew W. Johnson, Yu Jin Chung, M. Kate Curtis, Pete J. Cox, Kieran Clarke, Damian J. Tyler, David J. Roberts, Peter J. Ratcliffe, Keith L. Dorrington, Peter A. Robbins
Veröffentlicht in Scientific Reports (2022-01-01)

Publisher Correction: Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation

von Matthew C. Frise, David A. Holdsworth, Andrew W. Johnson, Yu Jin Chung, M. Kate Curtis, Pete J. Cox, Kieran Clarke, Damian J. Tyler, David J. Roberts, Peter J. Ratcliffe, Keith L. Dorrington, Peter A. Robbins
Veröffentlicht in Scientific Reports (2022-03-01)

Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases

von Rasheduzzaman Chowdhury, Ivanhoe K. H. Leung, Ya-Min Tian, Martine I. Abboud, Wei Ge, Carmen Domene, François-Xavier Cantrelle, Isabelle Landrieu, Adam P. Hardy, Christopher W. Pugh, Peter J. Ratcliffe, Timothy D. W. Claridge, Christopher J. Schofield
Veröffentlicht in Nature Communications (2016-08-01)

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain.

von Mun Chiang Chan, Onur Atasoylu, Emma Hodson, Anthony Tumber, Ivanhoe K H Leung, Rasheduzzaman Chowdhury, Verónica Gómez-Pérez, Marina Demetriades, Anna M Rydzik, James Holt-Martyn, Ya-Min Tian, Tammie Bishop, Timothy D W Claridge, Akane Kawamura, Christopher W Pugh, Peter J Ratcliffe, Christopher J Schofield
Veröffentlicht in PLoS ONE (2015-01-01)

Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology.

von Thomas G Smith, Jerome T Brooks, George M Balanos, Terence R Lappin, D Mark Layton, Dawn L Leedham, Chun Liu, Patrick H Maxwell, Mary F McMullin, Christopher J McNamara, Melanie J Percy, Christopher W Pugh, Peter J Ratcliffe, Nick P Talbot, Marilyn Treacy, Peter A Robbins
Veröffentlicht in PLoS Medicine (2006-07-01)

A Role for Cytosolic Fumarate Hydratase in Urea Cycle Metabolism and Renal Neoplasia

von Julie Adam, Ming Yang, Christina Bauerschmidt, Mitsuhiro Kitagawa, Linda O’Flaherty, Pratheesh Maheswaran, Gizem Özkan, Natasha Sahgal, Dilair Baban, Keiko Kato, Kaori Saito, Keiko Iino, Kaori Igarashi, Michael Stratford, Christopher Pugh, Daniel A. Tennant, Christian Ludwig, Benjamin Davies, Peter J. Ratcliffe, Mona El-Bahrawy, Houman Ashrafian, Tomoyoshi Soga, Patrick J. Pollard
Veröffentlicht in Cell Reports (2013-05-01)

Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells

von Peter A.C. Wing, Thomas P. Keeley, Xiaodong Zhuang, Jeffrey Y. Lee, Maria Prange-Barczynska, Senko Tsukuda, Sophie B. Morgan, Adam C. Harding, Isobel L.A. Argles, Samvid Kurlekar, Marko Noerenberg, Craig P. Thompson, Kuan-Ying A. Huang, Peter Balfe, Koichi Watashi, Alfredo Castello, Timothy S.C. Hinks, William James, Peter J. Ratcliffe, Ilan Davis, Emma J. Hodson, Tammie Bishop, Jane A. McKeating
Veröffentlicht in Cell Reports (2021-04-01)

Erythrocytosis associated with a novel missense mutation in the BPGM gene

von Nayia Petousi, Richard R. Copley, Terence R.J. Lappin, Sally E. Haggan, Celeste M. Bento, Holger Cario, Melanie J. Percy, The WGS Consortium, Peter J. Ratcliffe, Peter A. Robbins, Mary Frances McMullin, Peter Donnelly, John Bell, David Bentley, Gil McVean, Peter Ratcliffe, Jenny Taylor, Andrew Wilkie, Peter Donelly, John Broxholme, David Buck, Jean-Baptiste Cazier, Richard Cornall, Lorna Gregory, Julian Knight, Gerton Lunter, Gil McVean, Ian Tomlinson, Andrew Wilkie, David Buck, Christopher Allan, Moustafa Attar, Angie Green, Lorna Gregory, Sean Humphray, Zoya Kingsbury, Sarah Lamble, Lorne Lonie, Alistair Pagnamenta, Paolo Piazza, Guadelupe Polanco, Amy Trebes, Gil McVean, Peter Donnelly, Jean-Baptiste Cazier, John Broxholme, Richard Copley, Simon Fiddy, Russell Grocock, Edouard Hatton, Chris Holmes, Linda Hughes, Peter Humburg, Alexander Kanapin, Stefano Lise, Gerton Lunter, Hilary Martin, Lisa Murray, Davis McCarthy, Andy Rimmer, Natasha Sahgal, Ben Wright, Chris Yau
Veröffentlicht in Haematologica (2014-10-01)