Bibliotecas PUC-SP - Busca Integrada

Connections between ApoE, sleep, and Aβ and tau pathologies in Alzheimer’s disease

Yazar: Katherine R. Sadleir, Robert Vassar
Yayımlandı The Journal of Clinical Investigation (2023-07-01)

Oral nimodipine treatment has no effect on amyloid pathology or neuritic dystrophy in the 5XFAD mouse model of amyloidosis.

Yazar: Katherine R Sadleir, Jelena Popovic, Ammaarah Khatri, Robert Vassar
Yayımlandı PLoS ONE (2022-01-01)

ACE1 does not influence cerebral Aβ degradation or amyloid plaque accumulation in 5XFAD mice.

Yazar: Sohee Jeon, Alia O Alia, Jelena Popovic, Robert Vassar, Leah K Cuddy
Yayımlandı PLoS ONE (2025-01-01)

Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mous...

Yazar: Katherine R Sadleir, William A Eimer, Randal J Kaufman, Pavel Osten, Robert Vassar
Yayımlandı PLoS ONE (2014-01-01)

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

Yazar: Arun Upadhyay, Deepak Chhangani, Nalini R. Rao, Julia Kofler, Robert Vassar, Diego E. Rincon-Limas, Jeffrey N. Savas
Yayımlandı Molecular Neurodegeneration (2023-09-01)

BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice

Yazar: Masuo Ohno, Sarah L. Cole, Marina Yasvoina, Jie Zhao, Martin Citron, Robert Berry, John F. Disterhoft, Robert Vassar
Yayımlandı Neurobiology of Disease (2007-04-01)

Aberrant glial activation and synaptic defects in CaMKIIα-iCre and nestin-Cre transgenic mouse models

Yazar: Alia O. Alia, Sohee Jeon, Jelena Popovic, Miranda A. Salvo, Katherine R. Sadleir, Robert Vassar, Leah K. Cuddy
Yayımlandı Scientific Reports (2022-12-01)

BACE1 (β-secretase) knockout mice do not acquire compensatory gene expression changes or develop neural lesions over time

Yazar: Yi Luo, Brad Bolon, Michael A Damore, Dan Fitzpatrick, Hantao Liu, Jianhua Zhang, Qiao Yan, Robert Vassar, Martin Citron
Yayımlandı Neurobiology of Disease (2003-10-01)

The metabolism of human soluble amyloid precursor protein isoforms is quantifiable by a stable isotope labeling-tandem mass spectrometry method

Yazar: Justyna A. Dobrowolska Zakaria, Randall J. Bateman, Monika Lysakowska, Ammaarah Khatri, Dinorah Jean-Gilles, Matthew E. Kennedy, Robert Vassar
Yayımlandı Scientific Reports (2022-09-01)

Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection

Yazar: Tal Iram, Dorit Trudler, David Kain, Sivan Kanner, Ronit Galron, Robert Vassar, Ari Barzilai, Pablo Blinder, Zvi Fishelson, Dan Frenkel
Yayımlandı Neurobiology of Disease (2016-12-01)

A Becn1 mutation mediates hyperactive autophagic sequestration of amyloid oligomers and improved cognition in Alzheimer's disease.

Yazar: Altea Rocchi, Soh Yamamoto, Tabitha Ting, Yuying Fan, Katherine Sadleir, Yigang Wang, Weiran Zhang, Sui Huang, Beth Levine, Robert Vassar, Congcong He
Yayımlandı PLoS Genetics (2017-08-01)

Neuronal ACE1 knockout disrupts the hippocampal renin angiotensin system leading to memory impairment and vascular loss in normal aging

Yazar: Sohee Jeon, Miranda A. Salvo, Alia O. Alia, Jelena Popovic, Mitchell Zagardo, Sidhanth Chandra, Malik Nassan, David Gate, Robert Vassar, Leah K. Cuddy
Yayımlandı Neurobiology of Disease (2024-11-01)

Orally administrated cinnamon extract reduces β-amyloid oligomerization and corrects cognitive impairment in Alzheimer's disease animal models.

Yazar: Anat Frydman-Marom, Aviad Levin, Dorit Farfara, Tali Benromano, Roni Scherzer-Attali, Sivan Peled, Robert Vassar, Daniel Segal, Ehud Gazit, Dan Frenkel, Michael Ovadia
Yayımlandı PLoS ONE (2011-01-01)

Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice

Yazar: Leah K. Cuddy, Alia O. Alia, Miranda A. Salvo, Sidhanth Chandra, Tom N. Grammatopoulos, Craig J. Justman, Peter T. Lansbury, Joseph R. Mazzulli, Robert Vassar
Yayımlandı Molecular Neurodegeneration (2022-08-01)

The gut microbiome regulates astrocyte reaction to Aβ amyloidosis through microglial dependent and independent mechanisms

Yazar: Sidhanth Chandra, Antonio Di Meco, Hemraj B. Dodiya, Jelena Popovic, Leah K. Cuddy, Ian Q. Weigle, Xiaoqiong Zhang, Katherine Sadleir, Sangram S. Sisodia, Robert Vassar
Yayımlandı Molecular Neurodegeneration (2023-07-01)

The UNC5C T835M mutation associated with Alzheimer’s disease leads to neurodegeneration involving oxidative stress and hippocampal atrophy in aged mice

Yazar: Devi Krishna Priya Karunakaran, Makenna Ley, Joanna Guo, Ammaarah Khatri, Katherine Sadleir, Jelena Popovic, Arun Kumar Upadhyay, Jeffrey Savas, Daniele Procissi, Jasvinder Atwal, Robert Vassar
Yayımlandı Molecular Neurodegeneration (2025-06-01)

Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Yazar: Heather C. Rice, Gabriele Marcassa, Iordana Chrysidou, Katrien Horré, Tracy L. Young-Pearse, Ulrike C. Müller, Takashi Saito, Takaomi C. Saido, Robert Vassar, Joris de Wit, Bart De Strooper
Yayımlandı Molecular Neurodegeneration (2020-01-01)

Oxidative stress induced protein aggregation via GGCT produced pyroglutamic acid in drug resistant glioblastoma

Yazar: Deanna Tiek, Xiao Song, Xiaozhou Yu, Runxin Wu, Rebeca Iglesia, Alicia Catezone, Katy McCortney, Jordain Walshon, Craig Horbinski, Pouya Jamshidi, Rudolph Castellani, Robert Vassar, Jason Miska, Bo Hu, Shi-Yuan Cheng
Yayımlandı iScience (2025-02-01)

A Function for EHD Family Proteins in Unidirectional Retrograde Dendritic Transport of BACE1 and Alzheimer’s Disease Aβ Production

Yazar: Virginie Buggia-Prévot, Celia G. Fernandez, Vinod Udayar, Kulandaivelu S. Vetrivel, Aureliane Elie, Jelita Roseman, Verena A. Sasse, Margaret Lefkow, Xavier Meckler, Sohinee Bhattacharyya, Manju George, Satyabrata Kar, Vytautas P. Bindokas, Angèle T. Parent, Lawrence Rajendran, Hamid Band, Robert Vassar, Gopal Thinakaran
Yayımlandı Cell Reports (2013-12-01)

A conserved annexin A6–mediated membrane repair mechanism in muscle, heart, and nerve

Yazar: Alexis R. Demonbreun, Elena Bogdanovic, Lauren A. Vaught, Nina L. Reiser, Katherine S. Fallon, Ashlee M. Long, Claire C. Oosterbaan, Michele Hadhazy, Patrick G.T. Page, Prem Raj B. Joseph, Gabrielle Cowen, Alexander M. Telenson, Ammaarah Khatri, Katherine R. Sadleir, Robert Vassar, Elizabeth M. McNally
Yayımlandı JCI Insight (2022-07-01)