Bibliotecas PUC-SP - Busca Integrada

Activation anionique par les fluorures alcalins en milieu hétérogène : applications aux réactions d'hétérocyclisation.

Autor Sebti, Saïd
Vydáno n.d.

Étude des réactions en milieu hétérogène solide / liquide de l'hydroxyde de potassium et du fluorure de césium avec les acyloxy-2 chloro-3 propanamides et les acyloxy-2 chlor...

Autor Sebti, Saïd
Vydáno n.d.

Akt Mediates Ras Downregulation of RhoB, a Suppressor of Transformation, Invasion, and Metastasis

Autor Jiang, Kun, Sun, Jiazhi, Cheng, Jin, Djeu, Julie Y., Wei, Sheng, Sebti, Saïd
Vydáno 2004

Regulation of dendritic cell differentiation and antitumor immune response in cancer by pharmacological selective inhibition of the Jak2/STAT3 pathway

Autor Nefedova, Yulia, Nagaraj, Srinivas, Rosenbauer, Amsler, Muro-Cacho, Carlos, Sebti, Said M., Gabrilovich, Dmitry I.
Vydáno 2005

Activation of dendritic cells via inhibition of Jak2/STAT3 signaling

Autor Nefedova, Yulia, Cheng, Pingyan, Gilkes, Daniele, Blaskovich, Michelle, Beg, Amer A., Sebti, Said M., Gabrilovich, Dmitry I.
Vydáno 2005

Disruption of the Rb-Raf-1 Interaction Inhibits Tumor Growth and Angiogenesis

Autor Dasgupta, Piyali, Sun, Jiazhi, Wang, Sheng, Fusaro, Gina, Betts, Vicki, Padmanabhan, Jaya, Sebti, Saïd M., Chellappan, Srikumar P.
Vydáno 2004

The Phosphoinositide 3-OH Kinase/AKT2 Pathway as a Critical Target for Farnesyltransferase Inhibitor-Induced Apoptosis

Autor Jiang, Kun, Coppola, Domenico, Crespo, Nichole C., Nicosia, Santo V., Hamilton, Andrew D., Sebti, Said M., Cheng, Jin Q.
Vydáno 2000

Loss of Bif-1 Suppresses Bax/Bak Conformational Change and Mitochondrial Apoptosis

Autor Takahashi, Yoshinori, Karbowski, Mariusz, Yamaguchi, Hirohito, Kazi, Aslamuzzaman, Wu, Jie, Sebti, Saïd M., Youle, Richard J., Wang, Hong-Gang
Vydáno 2005

Geranylgeranyltransferase I Inhibitors Target RalB To Inhibit Anchorage-Dependent Growth and Induce Apoptosis and RalA To Inhibit Anchorage-Independent Growth

Autor Falsetti, Samuel C., Wang, De-an, Peng, Hairuo, Carrico, Dora, Cox, Adrienne D., Der, Channing J., Hamilton, Andrew D., Sebti, Saïd M.
Vydáno 2007

A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents

Autor Buckner, Frederick, Yokoyama, Kohei, Lockman, Jeffrey, Aikenhead, Kendra, Ohkanda, Junko, Sadilek, Martin, Sebti, Saïd, Van Voorhis, Wesley, Hamilton, Andrew, Gelb, Michael H.
Vydáno 2003

Colony-stimulating Factor-1 Receptor Utilizes Multiple Signaling Pathways to Induce Cyclin D2 Expression

Autor Dey, Arunangsu, She, Hongyun, Kim, Leopold, Boruch, Allan, Guris, Deborah L., Carlberg, Kristen, Sebti, Saïd M., Woodley, David T., Imamoto, Akira, Li, Wei
Vydáno 2000

Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104)

Autor Gajewski Thomas F, Salama April KS, Niedzwiecki Donna, Johnson Jeffrey, Linette Gerald, Bucher Cynthia, Blaskovich Michelle A, Sebti Said M, Haluska Frank
Vydáno v Journal of Translational Medicine (2012-12-01)

Targeting Protein-Protein Interactions: Suppression of Stat3 Dimerization with Rationally Designed Small-Molecule, Nonpeptidic SH2 Domain Binders

Autor Gunning, Patrick T., Glenn, Matthew P., Siddiquee, Khandaker A. Z., Katt, William P., Masson, Eric, Sebti, Saïd M., Turkson, James, Hamilton, Andrew D.
Vydáno 2008

Requirement for Ras/Rac1-Mediated p38 and c-Jun N-Terminal Kinase Signaling in Stat3 Transcriptional Activity Induced by the Src Oncoprotein

Autor Turkson, James, Bowman, Tammy, Adnane, Jalila, Zhang, Yi, Djeu, Julie Y., Sekharam, Madhavi, Frank, David A., Holzman, Lawrence B., Wu, Jie, Sebti, Said, Jove, Richard
Vydáno 1999

Blockade of Protein Geranylgeranylation Inhibits Cdk2-Dependent p27(Kip1) Phosphorylation on Thr187 and Accumulates p27(Kip1) in the Nucleus: Implications for Breast Cancer Therapy

Autor Kazi, Aslamuzzaman, Carie, Adam, Blaskovich, Michelle A., Bucher, Cynthia, Thai, Van, Moulder, Stacy, Peng, Hairuo, Carrico, Dora, Pusateri, Erin, Pledger, Warren J., Berndt, Norbert, Hamilton, Andrew, Sebti, Saïd M.
Vydáno 2009

Inhibitors of Src Homology-2 Domain containing Protein Tyrosine Phosphatase-2 (Shp2) Based on Oxindole Scaffolds

Autor Lawrence, Harshani R., Pireddu, Roberta, Chen, Liwei, Luo, Yunting, Sung, Shen-Shu, Szymanski, Ann Marie, Richard Yip, M. L., Guida, Wayne C., Sebti, Saïd M., Wu, Jie, Lawrence, Nicholas J.
Vydáno 2008

Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cell...

Autor Zhu, Kuichun, Gerbino, Elvira, Beaupre, Darrin M., Mackley, Paul A., Muro-Cacho, Carlos, Beam, Craig, Hamilton, Andrew D., Lichtenheld, Mathias G., Kerr, William G., Dalton, William, Alsina, Melissa, Sebti, Saïd M.
Vydáno 2005

Structural Basis for Binding and Selectivity of Antimalarial and Anticancer Ethylenediamine Inhibitors to Protein Farnesyltransferase

Autor Hast, Michael A., Fletcher, Steven, Cummings, Christopher G., Pusateri, Erin E., Blaskovich, Michelle A., Rivas, Kasey, Gelb, Michael H., Van Voorhis, Wesley C., Sebti, Said M., Hamilton, Andrew D., Beese, Lorena S.
Vydáno 2009

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

Autor Siddiquee, Khandaker, Zhang, Shumin, Guida, Wayne C., Blaskovich, Michelle A., Greedy, Benjamin, Lawrence, Harshani R., Yip, M. L. Richard, Jove, Richard, McLaughlin, Mark M., Lawrence, Nicholas J., Sebti, Said M., Turkson, James
Vydáno 2007

Identification of a Disruptor of the MDM2-p53 Protein-Protein Interaction Facilitated by High-throughput in Silico Docking

Autor Lawrence, Harshani R., Li, Zhenyu, Yip, M.L. Richard, Sung, Shen-Shu, Lawrence, Nicholas J., McLaughlin, Mark L., McManus, Gregory J., Zaworotko, Michael J., Sebti, Saïd M., Chen, Jiandong, Guida, Wayne C.
Vydáno 2009