Bibliotecas PUC-SP - Busca Integrada

The podoplanin-CLEC-2 axis inhibits inflammation in sepsis

par Julie Rayes, Siân Lax, Surasak Wichaiyo, Stephanie K. Watson, Ying Di, Stephanie Lombard, Beata Grygielska, Stuart W. Smith, Kassiani Skordilis, Steve P. Watson
Publié dans Nature Communications (2017-12-01)

The REFRACT trial: implementation of Bayesian power priors in a randomised, sequential phase II adaptive platform trial

par Charlotte Gaskell, Kim Linton, Mark Bishton, Graham McIlroy, Siân Lax, Sonia Fox, Louise Hopkins, Rebecca Collings, Malcolm Rhodes, Tania Seale, Aimee Jackson
Publié dans BMC Medical Research Methodology (2025-05-01)

Platelet glycoprotein VI and C-type lectin-like receptor 2 deficiency accelerates wound healing by impairing vascular integrity in mice

par Surasak Wichaiyo, Sian Lax, Samantha J. Montague, Zhi Li, Beata Grygielska, Jeremy A. Pike, Elizabeth J. Haining, Alexander Brill, Steve P. Watson, Julie Rayes
Publié dans Haematologica (2019-08-01)

A randomised phase II trial of temozolomide with or without cannabinoids in patients with recurrent glioblastoma (ARISTOCRAT): protocol for a multi-centre, double-blind, placebo-co...

par Divyalakshmi Bhaskaran, Joshua Savage, Amit Patel, Fiona Collinson, Rhys Mant, Florien Boele, Lucy Brazil, Sara Meade, Peter Buckle, Siân Lax, Lucinda Billingham, Susan C. Short
Publié dans BMC Cancer (2024-01-01)

The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent

par Julie Rayes, Soumaya Jadoui, Siân Lax, Angèle Gros, Surasak Wichaiyo, Véronique Ollivier, Cécile V. Denis, Jerry Ware, Bernhard Nieswandt, Martine Jandrot-Perrus, Steve P. Watson, Benoît Ho-Tin-Noé
Publié dans Haematologica (2018-06-01)

Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS

par Rahul Y. Mahida, Siân Lax, Christopher R. Bassford, Aaron Scott, Dhruv Parekh, Rowan S. Hardy, Babu Naidu, Michael A. Matthay, Paul M. Stewart, Mark C. Cooper, Gavin D. Perkins, David R. Thickett
Publié dans Frontiers in Immunology (2023-04-01)

Investigator choice of standard therapy versus sequential novel therapy arms in the treatment of relapsed follicular lymphoma (REFRACT): study protocol for a multi-centre, open-lab...

par Graham McIlroy, Siân Lax, Charlotte Gaskell, Aimee Jackson, Malcolm Rhodes, Tania Seale, Sonia Fox, Lousie Hopkins, Jessica Okosun, Sally F. Barrington, Ingo Ringshausen, Alan G. Ramsay, Maria Calaminici, Kim Linton, Mark Bishton
Publié dans BMC Cancer (2024-03-01)

A novel role for PECAM-1 (CD31) in regulating haematopoietic progenitor cell compartmentalization between the peripheral blood and bone marrow.

par Ewan A Ross, Sylvie Freeman, Yan Zhao, Tarvinder S Dhanjal, Emma J Ross, Sian Lax, Zubair Ahmed, Tie Zheng Hou, Neena Kalia, Stuart Egginton, Gerard Nash, Steve P Watson, Jon Frampton, Christopher D Buckley
Publié dans PLoS ONE (2008-06-01)

Lymphatic blood filling in CLEC-2-deficient mouse models

par Elizabeth J Haining, Kate L Lowe, Surasak Wichaiyo, Raghu P Kataru, Zoltan Nagy, Dean Pj Kavanagh, Sian Lax, Ying Di, Bernhard Nieswandt, Benoît Ho-Tin-Noé, Babak J Mehrara, Yotis A Senis, Julie Rayes, Steve P Watson
Publié dans Platelets (2021-04-01)

Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial

par Gideon M. Hirschfield, Katherine Arndtz, Amanda Kirkham, Yung-Yi Chen, Richard Fox, Anna Rowe, Jessica Douglas-Pugh, Douglas Thorburn, Eleanor Barnes, Guruprasad P. Aithal, Diana Hull, Khushpreet Bhandal, Kathryn Olsen, Paul Woodward, Siân Lax, Philip Newsome, David J. Smith, Antero Kallio, David H. Adams, Victoria Homer, Chris J. Weston
Publié dans Hepatology Communications (2024-05-01)

Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation

par Myriam Chimen, Aigli Evryviadou, Clare L. Box, Matthew J. Harrison, Jon Hazeldine, Lea H. Dib, Sahithi J. Kuravi, Holly Payne, Joshua M.J. Price, Dean Kavanagh, Asif J. Iqbal, Sian Lax, Neena Kalia, Alex Brill, Steve G. Thomas, Antonio Belli, Nicholas Crombie, Rachel A. Adams, Shelley-Ann Evans, Hans Deckmyn, Janet M. Lord, Paul Harrison, Steve P. Watson, Gerard B. Nash, G. Ed Rainger
Publié dans Haematologica (2020-05-01)