Bibliotecas PUC-SP - Busca Integrada

Changes in Oxidised Phospholipids in Response to Oxidative Stress in <i>Microtubule-Associated Protein Tau</i> (<i>MAPT</i>) Mutant Dopamine Neurons

Por Xanthe Bradford, Hugo J. R. Fernandes, Stuart G. Snowden
Publicado no Antioxidants (2024-04-01)

Metabolomic method: UPLC-q-ToF polar and non-polar metabolites in the healthy rat cerebellum using an in-vial dual extraction.

Por Amera A Ebshiana, Stuart G Snowden, Madhav Thambisetty, Richard Parsons, Abdul Hye, Cristina Legido-Quigley
Publicado no PLoS ONE (2015-01-01)

Dietary PUFAs drive diverse system-level changes in lipid metabolism

Por Samuel Furse, Samuel Virtue, Stuart G. Snowden, Antonio Vidal-Puig, Philip C. Stevenson, Davide Chiarugi, Albert Koulman
Publicado no Molecular Metabolism (2022-05-01)

Mitochondrial and Endoplasmic Reticulum Stress Trigger Triglyceride Accumulation in Models of Parkinson’s Disease Independent of Mutations in MAPT

Por Hugo J. R. Fernandes, Josh P. Kent, Michaela Bruntraeger, Andrew R. Bassett, Albert Koulman, Emmanouil Metzakopian, Stuart G. Snowden
Publicado no Metabolites (2023-01-01)

Systemic analyses show that the biosynthesis and spatial distribution of fatty acids, triglycerides and lipids differed in male and female mice and humans

Por Samuel Furse, Samuel Virtue, Isabel Huang-Doran, Antonio Vidal-Puig, Davide Chiarugi, Philip C. Stevenson, Stuart G. Snowden, Albert Koulman
Publicado no Open Biology (2025-08-01)

Development and Application of High-Throughput Single Cell Lipid Profiling: A Study of SNCA-A53T Human Dopamine Neurons

Por Stuart G. Snowden, Hugo J.R. Fernandes, Josh Kent, Stefanie Foskolou, Peri Tate, Sarah F. Field, Emmanouil Metzakopian, Albert Koulman
Publicado no iScience (2020-11-01)

Novel Metabolomic Approach for Identifying Pathology-Specific Biomarkers in Rare Diseases: A Case Study in Oculopharyngeal Muscular Dystrophy (OPMD)

Por Pradeep Harish, Alberto Malerba, Rosemarie H. M. J. M. Kroon, Milad Shademan, Baziel van Engelan, Vered Raz, Linda Popplewell, Stuart G. Snowden
Publicado no Metabolites (2023-06-01)

Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic study.

Por Stuart G Snowden, Amera A Ebshiana, Abdul Hye, Yang An, Olga Pletnikova, Richard O'Brien, John Troncoso, Cristina Legido-Quigley, Madhav Thambisetty
Publicado no PLoS Medicine (2017-03-01)

Lipid profiling analyses from mouse models and human infants

Por Laurentya Olga, Ivana Bobeldijk-Pastorova, Richard C. Bas, Florine Seidel, Stuart G. Snowden, Samuel Furse, Ken K. Ong, Robert Kleemann, Albert Koulman
Publicado no STAR Protocols (2022-12-01)

Evidence from 3-month-old infants shows that a combination of postnatal feeding and exposures in utero shape lipid metabolism

Por Samuel Furse, Stuart G. Snowden, Laurentya Olga, Philippa Prentice, Ken K. Ong, Ieuan A. Hughes, Carlo L. Acerini, David B. Dunger, Albert Koulman
Publicado no Scientific Reports (2019-10-01)

Metabolic phenotyping reveals a reduction in the bioavailability of serotonin and kynurenine pathway metabolites in both the urine and serum of individuals living with Alzheimer’s...

Por Luke Whiley, Katie E. Chappell, Ellie D’Hondt, Matthew R. Lewis, Beatriz Jiménez, Stuart G. Snowden, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Jonathan R. Swann, Abdul Hye, Simon Lovestone, Cristina Legido-Quigley, Elaine Holmes, on behalf of AddNeuroMed consortium
Publicado no Alzheimer’s Research & Therapy (2021-01-01)

Variants in mitochondrial amidoxime reducing component 1 and hydroxysteroid 17‐beta dehydrogenase 13 reduce severity of nonalcoholic fatty liver disease in children and suppress fi...

Por Christian A. Hudert, Leon A. Adams, Anna Alisi, Quentin M. Anstee, Annalisa Crudele, Laura G. Draijer, EU‐PNAFLD investigators, Samuel Furse, Jan G. Hengstler, Benjamin Jenkins, Kylie Karnebeek, Deirdre A. Kelly, Bart G. Koot, Albert Koulman, David Meierhofer, Phillip E. Melton, Trevor A. Mori, Stuart G. Snowden, Indra vanMourik, Anita Vreugdenhil, Susanna Wiegand, Jake P. Mann
Publicado no Hepatology Communications (2022-08-01)

Sex-Specific Metabolic Pathways Were Associated with Alzheimer’s Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Coh...

Por Jin Xu, Rebecca Green, Min Kim, Jodie Lord, Amera Ebshiana, Sarah Westwood, Alison L. Baird, Alejo J. Nevado-Holgado, Liu Shi, Abdul Hye, Stuart G. Snowden, Isabelle Bos, Stephanie J. B. Vos, Rik Vandenberghe, Charlotte E. Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen Elisa De Roeck, Sebastiaan Engelborghs, Kristel Sleegers, Régis Bordet, Lorena Rami, Petronella Kettunen, Magda Tsolaki, Frans R. J. Verhey, Daniel Alcolea, Alberto Lleó, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Giovanni B. Frisoni, José Luis Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez-Lage, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone, Petroula Proitsi, Cristina Legido-Quigley, on behalf of the European Medical Information Framework Consortium
Publicado no Biomedicines (2021-11-01)