Bibliotecas PUC-SP - Busca Integrada

From hypoxia single‐cell gene signatures to HIF targeting of AML leukemic stem cells

Por Thomas Mercher, Juerg Schwaller
Publicado no HemaSphere (2024-03-01)

Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention

Por Thomas Mercher, Juerg Schwaller
Publicado no Frontiers in Pediatrics (2019-10-01)

Corrigendum: Pediatric Acute Myeloid Leukemia (AML): From Genes to Models Toward Targeted Therapeutic Intervention

Por Thomas Mercher, Juerg Schwaller
Publicado no Frontiers in Pediatrics (2019-11-01)

NUP98 and KMT2A: usually the bride rather than the bridesmaid

Por Alexandre Fagnan, Thomas Mercher
Publicado no Haematologica (2020-07-01)

Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia

Por Cécile Thirant, Cécile Lopez, Sébastien Malinge, Thomas Mercher
Publicado no Molecular & Cellular Oncology (2017-11-01)

Molecular Landscapes and Models of Acute Erythroleukemia

Por Alexandre Fagnan, Maria-Riera Piqué-Borràs, Samantha Tauchmann, Thomas Mercher, Juerg Schwaller
Publicado no HemaSphere (2021-05-01)

JAM-C/Jam-C Expression Is Primarily Expressed in Mouse Hematopoietic Stem Cells

Por Elia Henry, Vilma Barroca, Cécile K. Lopez, Michel Aurrand-Lions, Daniel Lewandowski, Thomas Mercher, Marie-Laure Arcangeli
Publicado no HemaSphere (2021-07-01)

Chromosomal Translocation Formation Is Sufficient to Produce Fusion Circular RNAs Specific to Patient Tumor Cells

Por Loelia Babin, Marion Piganeau, Benjamin Renouf, Khadija Lamribet, Cecile Thirant, Ludovic Deriano, Thomas Mercher, Carine Giovannangeli, Erika C. Brunet
Publicado no iScience (2018-07-01)

Partial trisomy 21 contributes to T-cell malignancies induced by JAK3-activating mutations in murine models

Por Paola Rivera-Munoz, Anouchka P. Laurent, Aurelie Siret, Cecile K. Lopez, Cathy Ignacimouttou, Melanie G. Cornejo, Olivia Bawa, Philippe Rameau, Olivier A. Bernard, Philippe Dessen, Gary D. Gilliland, Thomas Mercher, Sébastien Malinge
Publicado no Blood Advances (2018-07-01)

Nuclear interacting SET domain protein 1 inactivation impairs GATA1-regulated erythroid differentiation and causes erythroleukemia

Por Katharina Leonards, Marwa Almosailleakh, Samantha Tauchmann, Frederik Otzen Bagger, Cécile Thirant, Sabine Juge, Thomas Bock, Hélène Méreau, Matheus F. Bezerra, Alexandar Tzankov, Robert Ivanek, Régine Losson, Antoine H. F. M. Peters, Thomas Mercher, Juerg Schwaller
Publicado no Nature Communications (2020-06-01)

Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis

Por Sumin Koo, Brian J. Huntly, Yuan Wang, Jing Chen, Kristina Brumme, Brian Ball, Shannon L. McKinney-Freeman, Akiko Yabuuchi, Claudia Scholl, Dimple Bansal, Leonard I. Zon, Stefan Fröhling, George Q. Daley, D. Gary Gilliland, Thomas Mercher
Publicado no Haematologica (2010-10-01)

The Pediatric Acute Leukemia Fusion Oncogene ETO2-GLIS2 Increases Self-Renewal and Alters Differentiation in a Human Induced Pluripotent Stem Cells-Derived Model

Por Salvatore Nicola Bertuccio, Fabien Boudia, Marie Cambot, Cécile K. Lopez, Larissa Lordier, Alessandro Donada, Elie Robert, Cécile Thirant, Zakia Aid, Salvatore Serravalle, Annalisa Astolfi, Valentina Indio, Franco Locatelli, Andrea Pession, William Vainchenker, Riccardo Masetti, Hana Raslova, Thomas Mercher
Publicado no HemaSphere (2020-02-01)

B-cell tumor development in Tet2-deficient mice

Por Enguerran Mouly, Hussein Ghamlouch, Veronique Della-Valle, Laurianne Scourzic, Cyril Quivoron, Damien Roos-Weil, Patrycja Pawlikowska, Véronique Saada, M'Boyba K. Diop, Cécile K. Lopez, Michaela Fontenay, Philippe Dessen, Ivo P. Touw, Thomas Mercher, Said Aoufouchi, Olivier A. Bernard
Publicado no Blood Advances (2018-03-01)

De novo generation of the NPM-ALK fusion recapitulates the pleiotropic phenotypes of ALK+ ALCL pathogenesis and reveals the ROR2 receptor as target for tumor cells

Por Loélia Babin, Alice Darchen, Elie Robert, Zakia Aid, Rosalie Borry, Claire Soudais, Marion Piganeau, Anne De Cian, Carine Giovannangeli, Olivia Bawa, Charlotte Rigaud, Jean-Yves Scoazec, Lucile Couronné, Layla Veleanu, Agata Cieslak, Vahid Asnafi, David Sibon, Laurence Lamant, Fabienne Meggetto, Thomas Mercher, Erika Brunet
Publicado no Molecular Cancer (2022-03-01)

MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.

Por Yana Pikman, Benjamin H Lee, Thomas Mercher, Elizabeth McDowell, Benjamin L Ebert, Maricel Gozo, Adam Cuker, Gerlinde Wernig, Sandra Moore, Ilene Galinsky, Daniel J DeAngelo, Jennifer J Clark, Stephanie J Lee, Todd R Golub, Martha Wadleigh, D Gary Gilliland, Ross L Levine
Publicado no PLoS Medicine (2006-07-01)

Developmental interplay between transcriptional alterations and a targetable cytokine signaling dependency in pediatric ETO2::GLIS2 leukemia

Por Verónica Alonso-Pérez, Klaudia Galant, Fabien Boudia, Elie Robert, Zakia Aid, Laurent Renou, Vilma Barroca, Saryiami Devanand, Loélia Babin, Virginie Rouiller-Fabre, Delphine Moison, Didier Busso, Guillaume Piton, Christophe Metereau, Nassera Abermil, Paola Ballerini, Pierre Hirsch, Rima Haddad, Jelena Martinovic, Arnaud Petit, Hélène Lapillonne, Erika Brunet, Thomas Mercher, Françoise Pflumio
Publicado no Molecular Cancer (2024-09-01)

STAT3 mutations identified in human hematologic neoplasms induce myeloid malignancies in a mouse bone marrow transplantation model

Por Lucile Couronné, Laurianne Scourzic, Camilla Pilati, Véronique Della Valle, Yannis Duffourd, Eric Solary, William Vainchenker, Jean-Philippe Merlio, Marie Beylot-Barry, Frederik Damm, Marc-Henri Stern, Philippe Gaulard, Laurence Lamant, Eric Delabesse, Hélène Merle-Beral, Florence Nguyen-Khac, Michaëla Fontenay, Hervé Tilly, Christian Bastard, Jessica Zucman-Rossi, Olivier A. Bernard, Thomas Mercher
Publicado no Haematologica (2013-11-01)

The ETO2 transcriptional cofactor maintains acute leukemia by driving a MYB/EP300‐dependent stemness program

Por Alexandre Fagnan, Zakia Aid, Marie Baille, Aneta Drakul, Elie Robert, Cécile K. Lopez, Cécile Thirant, Yann Lecluse, Julie Rivière, Cathy Ignacimouttou, Silvia Salmoiraghi, Eduardo Anguita, Audrey Naimo, Christophe Marzac, Françoise Pflumio, Sébastien Malinge, Christian Wichmann, Yun Huang, Camille Lobry, Julie Chaumeil, Eric Soler, Jean‐Pierre Bourquin, Claus Nerlov, Olivier A. Bernard, Juerg Schwaller, Thomas Mercher
Publicado no HemaSphere (2024-06-01)

Stepwise GATA1 and SMC3 mutations alter megakaryocyte differentiation in a Down syndrome leukemia model

Por Brahim Arkoun, Elie Robert, Fabien Boudia, Stefania Mazzi, Virginie Dufour, Aurélie Siret, Yasmine Mammasse, Zakia Aid, Matthieu Vieira, Aygun Imanci, Marine Aglave, Marie Cambot, Rachel Petermann, Sylvie Souquere, Philippe Rameau, Cyril Catelain, Romain Diot, Gérard Tachdjian, Olivier Hermine, Nathalie Droin, Najet Debili, Isabelle Plo, Sébastien Malinge, Eric Soler, Hana Raslova, Thomas Mercher, William Vainchenker
Publicado no The Journal of Clinical Investigation (2023-04-01)

Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia

Por Shannon L. Carey-Smith, Maryam H. Simad, Kunjal Panchal, Carlos Aya-Bonilla, Hannah Smolders, Sang Lin, Jesse D. Armitage, Vivien T. Nguyen, Kathryn Bentley, Jette Ford, Sajla Singh, Joyce Oommen, Anouchka P. Laurent, Thomas Mercher, John D. Crispino, Andrew P. Montgomery, Michael Kassiou, Thierry Besson, Emmanuel Deau, Laurent Meijer, Laurence C. Cheung, Rishi S. Kotecha, Sébastien Malinge
Publicado no Haematologica (2024-02-01)