Bibliotecas PUC-SP - Busca Integrada

Cell surface-bound TIMP3 induces apoptosis in mesenchymal Cal78 cells through ligand-independent activation of death receptor signaling and blockade of survival pathways.

Por Christina Koers-Wunrau, Corinna Wehmeyer, Anja Hillmann, Thomas Pap, Berno Dankbar
Publicado no PLoS ONE (2013-01-01)

Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts

Por Saliha Harrach, Bayram Edemir, Christian Schmidt-Lauber, Thomas Pap, Jessica Bertrand, Giuliano Ciarimboli
Publicado no Scientific Reports (2017-04-01)

Loss of the WNT9a ligand aggravates the rheumatoid arthritis-like symptoms in hTNF transgenic mice

Por Stefan Teufel, Petra Köckemann, Christine Fabritius, Lena I. Wolff, Jessica Bertrand, Thomas Pap, Christine Hartmann
Publicado no Cell Death and Disease (2021-05-01)

Chondrocytes From Osteoarthritic and Chondrocalcinosis Cartilage Represent Different Phenotypes

Por Franziska Meyer, Annalena Dittmann, Uwe Kornak, Maria Herbster, Thomas Pap, Christoph H. Lohmann, Jessica Bertrand
Publicado no Frontiers in Cell and Developmental Biology (2021-04-01)

Toll-like receptor 3 activation promotes joint degeneration in osteoarthritis

Por Josef Stolberg-Stolberg, Annika Boettcher, Meike Sambale, Sina Stuecker, Joanna Sherwood, Michael Raschke, Thomas Pap, Jessica Bertrand
Publicado no Cell Death and Disease (2022-03-01)

Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents

Por Josef Stolberg-Stolberg, Meike Sambale, Uwe Hansen, Alexandra Schäfer Michael Raschke, Jessica Bertrand, Thomas Pap, Joanna Sherwood
Publicado no International Journal of Molecular Sciences (2020-06-01)

A Novel Role of IGF1 in Apo2L/TRAIL-Mediated Apoptosis of Ewing Tumor Cells

Por Frans van Valen, Henning Harrer, Marc Hotfilder, Uta Dirksen, Thomas Pap, George Gosheger, Hans-Ulrich Humpf, Heribert Jürgens
Publicado no Sarcoma (2012-01-01)

A myostatin-CCL20–CCR6 axis regulates Th17 cell recruitment to inflamed joints in experimental arthritis

Por Michelle Fennen, Toni Weinhage, Vanessa Kracke, Johanna Intemann, Georg Varga, Corinna Wehmeyer, Dirk Foell, Adelheid Korb-Pap, Thomas Pap, Berno Dankbar
Publicado no Scientific Reports (2021-07-01)

Microsurgical reconstruction affects the outcome in a translational mouse model for Achilles tendon healing

Por Philipp A. Michel, Daniel Kronenberg, Gertje Neu, Josef Stolberg-Stolberg, Andre Frank, Thomas Pap, Martin Langer, Michael Fehr, Michael J. Raschke, Richard Stange
Publicado no Journal of Orthopaedic Translation (2020-09-01)

Oral enzyme combination therapy reduces systemic inflammation, urinary CTXII and pain in knee osteoarthritis: a proof-of-mechanism, randomised, crossover, double-blind, placebo-con...

Por Thomas Pap, Odd Erik Johansen, Yves Henrotin, Valérie Badot, Stefanie Rau, Maximilian von Eynatten, Jean-Emile Dubuc, Siddhartha Lieten, Didier Urbin-Choffray, Karl Brabants
Publicado no RMD Open (2025-08-01)

Microvascular immunity is organ-specific and remodeled after kidney injury in mice

Por Rebecca Rixen, Paula Schütz, Carolin Walter, Birte Hüchtmann, Veerle Van Marck, Barbara Heitplatz, Julian Varghese, Georg Varga, Dirk Foell, Thomas Pap, Hermann Pavenstädt, Konrad Buscher
Publicado no Nature Communications (2025-05-01)

The activin-follistatin anti-inflammatory cycle is deregulated in synovial fibroblasts

Por Magnus Diller, Klaus Frommer, Berno Dankbar, Ingo Tarner, Marie-Lisa Hülser, Lali Tsiklauri, Rebecca Hasseli, Michael Sauerbier, Thomas Pap, Stefan Rehart, Ulf Müller-Ladner, Elena Neumann
Publicado no Arthritis Research & Therapy (2019-06-01)

Inhibition of histone deacetylase 6 suppresses inflammatory responses and invasiveness of fibroblast-like-synoviocytes in inflammatory arthritis

Por Jin Kyun Park, Sehui Shon, Hyun Jung Yoo, Dong-Hyeon Suh, Daekwon Bae, Jieun Shin, Jae Hyun Jun, Nina Ha, Hyeseung Song, Young Il Choi, Thomas Pap, Yeong Wook Song
Publicado no Arthritis Research & Therapy (2021-07-01)

Hem1 is essential for ruffled border formation in osteoclasts and efficient bone resorption

Por Eugenie Werbenko, David J. J. de Gorter, Simon Kleimann, Denise Beckmann, Vanessa Waltereit-Kracke, Julia Reinhardt, Fabienne Geers, Peter Paruzel, Uwe Hansen, Thomas Pap, Theresia E. B. Stradal, Berno Dankbar
Publicado no Scientific Reports (2024-04-01)

Transport mechanisms and their pathology-induced regulation govern tyrosine kinase inhibitor delivery in rheumatoid arthritis.

Por Christian Schmidt-Lauber, Saliha Harrach, Thomas Pap, Meike Fischer, Marion Victor, Marianne Heitzmann, Uwe Hansen, Manfred Fobker, Stefan-Martin Brand, Aleksandra Sindic, Hermann Pavenstädt, Bayram Edemir, Eberhard Schlatter, Jessica Bertrand, Giuliano Ciarimboli
Publicado no PLoS ONE (2012-01-01)

IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes

Por Michael Bonelli, Karolina Dalwigk, Alexander Platzer, Isabel Olmos Calvo, Silvia Hayer, Birgit Niederreiter, Johannes Holinka, Florian Sevelda, Thomas Pap, Günter Steiner, Giulio Superti-Furga, Josef S. Smolen, Hans P. Kiener, Thomas Karonitsch
Publicado no Experimental and Molecular Medicine (2019-07-01)

TRPC1 links calcium signaling to cellular senescence in the protection against posttraumatic osteoarthritis

Por Meike Sambale, Starlee Lively, Osvaldo Espin-Garcia, Pratibha Potla, Chiara Pastrello, Sarah Bödecker, Linda Wessendorf, Simon Kleimann, Peter Paruzel, Rojiar Asgarian, Alexandra Tosun, Johanna Intemann, Jessica Bertrand, Francesco Dell’Accio, Mohit Kapoor, Thomas Pap, Joanna Sherwood
Publicado no JCI Insight (2025-02-01)

Disease modification and symptom relief in osteoarthritis using a mutated GCP‐2/CXCL6 chemokine

Por Sara Caxaria, Nikolaos Kouvatsos, Suzanne E Eldridge, Mario Alvarez‐Fallas, Anne‐Sophie Thorup, Daniela Cici, Aida Barawi, Ammaarah Arshed, Danielle Strachan, Giulia Carletti, Xinying Huang, Sabah Bharde, Melody Deniz, Jacob Wilson, Bethan L Thomas, Costantino Pitzalis, Francesco Paolo Cantatore, Manasi Sayilekshmy, Shafaq Sikandar, Frank P Luyten, Thomas Pap, Joanna C Sherwood, Anthony J Day, Francesco Dell'Accio
Publicado no EMBO Molecular Medicine (2022-12-01)

CRUP: a comprehensive framework to predict condition-specific regulatory units

Por Anna Ramisch, Verena Heinrich, Laura V. Glaser, Alisa Fuchs, Xinyi Yang, Philipp Benner, Robert Schöpflin, Na Li, Sarah Kinkley, Anja Römer-Hillmann, John Longinotto, Steffen Heyne, Beate Czepukojc, Sonja M. Kessler, Alexandra K. Kiemer, Cristina Cadenas, Laura Arrigoni, Nina Gasparoni, Thomas Manke, Thomas Pap, John A. Pospisilik, Jan Hengstler, Jörn Walter, Sebastiaan H. Meijsing, Ho-Ryun Chung, Martin Vingron
Publicado no Genome Biology (2019-11-01)

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Por Kerstin Göbel, Susann Pankratz, Chloi-Magdalini Asaridou, Alexander M. Herrmann, Stefan Bittner, Monika Merker, Tobias Ruck, Sarah Glumm, Friederike Langhauser, Peter Kraft, Thorsten F. Krug, Johanna Breuer, Martin Herold, Catharina C. Gross, Denise Beckmann, Adelheid Korb-Pap, Michael K. Schuhmann, Stefanie Kuerten, Ioannis Mitroulis, Clemens Ruppert, Marc W. Nolte, Con Panousis, Luisa Klotz, Beate Kehrel, Thomas Korn, Harald F. Langer, Thomas Pap, Bernhard Nieswandt, Heinz Wiendl, Triantafyllos Chavakis, Christoph Kleinschnitz, Sven G. Meuth
Publicado no Nature Communications (2016-05-01)