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The effects of mutagenesis on the reactive centre loop of two thrombin-inhibitory serpins, antithrombin and heparin cofactor II

<p>Antithrombin (AT) and heparin cofactor II (HCII) are the predominant inhibitors of thrombin in plasma. They belong to the se rine p[barbelow]rotease in hibitor, or serpin, family of proteins and they inhibit their target proteases through a mechanism that is unique to this family of molecul...

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Glavni avtor: Cunningham, Andrew Michael
Drugi avtorji: Sheffield, W.P.
Format: Online
Izdano: 2014
Teme:
Online dostop:http://hdl.handle.net/11375/7392
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