Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

<p>Abstract</p> <p>Background</p> <p>The Nef protein of HIV facilitates virus replication and disease progression in infected patients. This role as pathogenesis factor depends on several genetically separable Nef functions that are mediated by interactions of highly co...

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Publicado no:Retrovirology
Main Authors: Meuwissen Pieter J, Stolp Bettina, Iannucci Veronica, Vermeire Jolien, Naessens Evelien, Saksela Kalle, Geyer Matthias, Vanham Guido, Arien Kevin K, Fackler Oliver T, Verhasselt Bruno
Formato: Artigo
Publicado em: BMC 2012-04-01
Assuntos:
HIV
Nef
Sequence motifs
SH3 domain binding
Cytoskeleton
Lck
Receptor downregulation
Infectivity
Replication
Acesso em linha:http://www.retrovirology.com/content/9/1/34
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http://www.retrovirology.com/content/9/1/34

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