Preparation of a Zirconium-89 Labeled Clickable DOTA Complex and Its Antibody Conjugate

Desferrioxamine B (DFO) is the clinical standard chelator for preparing zirconium-89 labeled antibodies. In the current study, the stabilities of a zirconium-89 labeled panitumumab (PAN; Vectibix<sup>®</sup>) with three different chelators (DFO, DFO*, and DOTA) were compared. PAN is an a...

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Bibliografiska uppgifter
I publikationen:Pharmaceuticals
Huvudupphovsmän: Falguni Basuli, Olga Vasalatiy, Jianfeng Shi, Kelly C. Lane, Freddy E. Escorcia, Rolf E. Swenson
Materialtyp: Artikel
Publicerad: MDPI AG 2024-04-01
Ämnen:
DOTA
BCN-DOTA-GA
PAN
DFO
DFO*
Stability
Länkar:https://www.mdpi.com/1424-8247/17/4/480
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