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Trained Immunity Enhances Human Monocyte Function in Aging and Sepsis

Aging plays a critical role in the incidence and severity of infection, with age emerging as an independent predictor of mortality in sepsis. Trained immunity reprograms immunocytes to respond more rapidly and effectively to pathogens and serves as a potential approach to improve immune function in...

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Udgivet i:Frontiers in Immunology
Main Authors: P. Spencer Gill, Tammy R. Ozment, Nicole H. Lewis, Edward R. Sherwood, David L. Williams
Format: Artigo
Udgivet: Frontiers Media S.A. 2022-05-01
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Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2022.872652/full
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