SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells

Blood cell generation depends on continuous cellular output by the sequential hierarchy of hematopoietic stem cell (HSC) and progenitor populations that all contain quiescent and actively cycling cells. Hematopoietic stem and progenitor cells (HSPCs) express the surface molecule Stem cell antigen 1...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Mina N.F. Morcos, Kristina B. Schoedel, Anja Hoppe, Rayk Behrendt, Onur Basak, Hans C. Clevers, Axel Roers, Alexander Gerbaulet
Formato: Artigo
Publicado em: Elsevier 2017-06-01
Assuntos:
Hematopoeitic stem cells
Hematopoeitic progenitor cells
Type I interferon
Hematopoietic stem and progenitor cell purification and analysis
Hematopoietic stem and progenitor cell potential
Hematopoietic stem and progenitor cell heterogeneity
Cell cycle
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213671117301662
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