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An iPSC model for POLR3A-associated spastic ataxia: Generation of three unrelated patient cell lines

Spastic Ataxias (SA) are a group of neurodegenerative disorders with combined pyramidal and cerebellar system affection, leading to an overlap phenotype between Hereditary Spastic Paraplegias (HSP) and Cerebellar Ataxias (CA). Here we describe the generation of iPSCs from three unrelated patients wi...

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Pubblicato in:Stem Cell Research
Autori principali: Kalaivani Manibarathi, Tam Pham, Holger Hengel, Matthis Synofzik, Maike Nagel, Rebecca Schüle
Natura: Articolo
Pubblicazione: Elsevier 2024-04-01
Accesso online:http://www.sciencedirect.com/science/article/pii/S1873506124000618
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